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Details for Patent: 6,699,503

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Summary for Patent: 6,699,503

Title: Hydrogel-forming sustained-release preparation
Abstract:The invention provides a hydrogen-type sustained-release preparation comprising (1) at least one drug, (2) an additive which insures a penetration of water into the core of the preparation and (3) a hydrogen-forming polymer, wherein said preparation is capable of undergoing substantially complete gelation during its stay in the upper digestive tract such as stomach and small intestine and is capable of releasing the drug in the lower digestive tract including colon. By the preparation of the invention, the drug is efficiently released and absorbed even in the colon so that a steady and sustained release effect can be achieved.
Inventor(s): Sako; Kazuhiro (Shizuoka, JP), Nakashima; Hiroshi (Shizuoka, JP), Sawada; Toyohiro (Shizuoka, JP), Okada; Akira (Shizuoka, JP), Fukui; Muneo (Shizuoka, JP)
Assignee: Yamanuchi Pharmaceutical Co., Ltd. (Tokyo, JP)
Application Number:09/702,880
Patent Claim Types:
see list of patent claims
Patent PDF download available with subscription

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Foreign Priority and PCT Information for Patent: 6,699,503

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan4-274979Sep 18, 1992
Japan5-165263Jun 08, 1993

International Patent Family for Patent: 6,699,503

Country Document Number Publication Date
South Africa9306798Apr 14, 1994
World Intellectual Property Organization (WIPO)9406414Mar 31, 1994
United States of America6436441Aug 20, 2002
United States of America2003203024Oct 30, 2003
Taiwan393320Jun 11, 2000
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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