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Details for Patent: 6,403,649

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Summary for Patent: 6,403,649

Title: Non-acidic cyclopentane heptanoic acid,2-cycloalkyl or arylalkyl derivatives as therapeutic agents
Abstract:The present invention provides cydopentane heptanoic acid, 2-cycloalkyl or arylalkyl compounds, which may be substituted in the 1-position with amino, amido, ether or ester groups, e.g., a 1-OH cydopentane heptanoic acid, 2-(cycloalkyl or arylalkyl) compound. The cydopentane heptanoic acid, 2-(cycloalkyl or arylalkyl) compounds of the present invention are potent ocular hypotensives, and are particularly suitable for the management of glaucoma. Moreover, the cydopentane heptanoic, 2-(cycloalkyl or arylalkyl) compounds of this invention are smooth muscle relaxants with broad application in systemic hypertensive and pulmonary diseases; smooth muscle relaxants with application in gastrointestinal disease, reproduction, fertility, incontinence, shock, etc.
Inventor(s): Woodward; David F. (El Toro, CA), Andrews; Steven W. (Rancho Santa Marguerita, CA), Burk; Robert M. (Irvine, CA), Garst; Michael E. (Newport Beach, CA)
Assignee: Allergan Sales, Inc. (Irvine, CA)
Application Number:09/519,834
Patent Claim Types:
see list of patent claims
Compound; Use;
Patent PDF download available with subscription

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International Patent Family for Patent: 6,403,649

Country Document Number Publication Date
World Intellectual Property Organization (WIPO)9406433Mar 31, 1994
World Intellectual Property Organization (WIPO)9636599Nov 21, 1996
World Intellectual Property Organization (WIPO)9730710Aug 28, 1997
United States of America5352708Oct 04, 1994
United States of America5607978Mar 04, 1997
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