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Details for Patent: 6,291,488

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Summary for Patent: 6,291,488

Title: Preventing protozoal infections
Abstract:The invention relates to combinations of atovaquone and proguanil, their use in the treatment and prophylaxis of parasitic infections such as protozoal parasitic infections, e.g., malaria and toxoplasmosis, and infections caused by P. carinii and their use in the manufacture of medicaments for the treatment and/or prophylaxis of such infections. The combinations can conveniently be administered in a single pharmaceutical formulation. Preferably, atovaquone and proguanil are administered in a potentiating ratio so that they act in synergy.
Inventor(s): Gutteridge; Winston Edward (Beckenham, GB), Hutchinson; David Brian Ashton (Beckenham, GB), Latter; Victoria Susan (Beckenham, GB), Pudney; Mary (Beckenham, GB)
Assignee: Glaxo Wellcome Inc. (Research Triangle Park, NC)
Application Number:09/678,485
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Glaxosmithkline
MALARONE
atovaquone; proguanil hydrochloride
TABLET;ORAL021078Jul 14, 2000RXYes6,291,488*PED<disabled>Y
Glaxosmithkline
MALARONE PEDIATRIC
atovaquone; proguanil hydrochloride
TABLET;ORAL021078Jul 14, 2000RXNo6,291,488*PED<disabled>Y
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Foreign Priority and PCT Information for Patent: 6,291,488

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9224739Nov 26, 1992

International Patent Family for Patent: 6,291,488

Country Document Number Publication Date
South Africa9308832May 25, 1995
World Intellectual Property Organization (WIPO)9412680Jun 09, 1994
World Intellectual Property Organization (WIPO)9412164Jun 09, 1994
United States of America5998449Dec 07, 1999
United States of America6166046Dec 26, 2000
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