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Details for Patent: 5,958,961

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Summary for Patent: 5,958,961

Title: Pharmaceutical composition for angiotensin II-mediated diseases
Abstract:This invention relates to a pharmaceutical composition for angiotensin II-mediated diseases, which comprises a compound having angiotensin II antagonistic activity of the formula ##STR1## wherein R.sup.1 is H or an optionally substituted hydrocarbon residue; R.sup.2 is an optionally esterified carboxyl group; R.sup.3 is a group capable of forming an anion or a group convertible thereinto; X is a covalent bond between the 2 phenyl rings or a spacer having a chain length of 1 to 2 atoms as the linear moiety between the adjoining phenylene group and phenyl group; n is 1 or 2; the ring A is a benzene ring having 1 or 2 optional substituents in addition to R.sup.2 ; and Y is a bond, --O--, --S(O)m- (wherein m is 0, 1 or 2) or --N(R.sup.4)-- (wherein R.sup.4 is H or an optionally substituted alkyl group), or a pharmaceutically acceptable salt thereof in combination with a compound having diuretic activity or a compound having calcium antagonistic activity.
Inventor(s): Inada; Yoshiyuki (Kawanishi, JP), Kubo; Keiji (Riverside, CA)
Assignee: Takeda Chemical Industries, Ltd. (Osaka, JP)
Application Number:08/883,040
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;
Patent PDF download available with subscription

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Foreign Priority and PCT Information for Patent: 5,958,961

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan5-133524Jun 07, 1993

International Patent Family for Patent: 5,958,961

Country Document Number Publication Date
United States of America6228874May 08, 2001
United States of America5721263Feb 24, 1998
United States of America2001004640Jun 21, 2001
United States of America6348481Feb 19, 2002
United States of America2001011098Aug 02, 2001
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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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