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Details for Patent: 5,919,455

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Summary for Patent: 5,919,455

Title: Non-antigenic branched polymer conjugates
Abstract:Branched, substantially non-antigenic polymers are disclosed. Conjugates prepared with the polymers and biologically active molecules such as proteins and peptides demonstrate extended circulating life in vivo. Substantially fewer sites on the biologically active material are used as attachment sites. Methods of forming the polymer, conjugating the polymers with biologically active moieties and methods of using the conjugates are also disclosed.
Inventor(s): Greenwald; Richard B. (Somerset, NJ), Martinez; Anthony J. (Hamilton Square, NJ)
Assignee: Enzon, Inc. (Piscataway, NJ)
Application Number:08/821,055
Patent Claim Types:
see list of patent claims
Compound; Use;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Valeant Pharms Llc
MACUGEN
pegaptanib sodium
INJECTABLE;INTRAVITREAL021756Dec 17, 2004RXYes5,919,455<disabled>Y
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International Patent Family for Patent: 5,919,455

Country Document Number Publication Date
WIPO (PCT)9511924May 04, 1995
WIPO (PCT)9841562Sep 24, 1998
United States5605976Feb 25, 1997
United States5643575Jul 01, 1997
United States5681567Oct 28, 1997
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