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Details for Patent: 5,543,152

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Patent 5,543,152 protects MARQIBO KIT and is included in one NDA.

Summary for Patent: 5,543,152

Title: Sphingosomes for enhanced drug delivery
Abstract:Liposomal formulations having extended circulation time in vivo and increased drug retention are comprised of sphingomyelin and cholesterol and have an acidic intraliposomal pH. The formulations have enhanced stability and thus are used in methods which provide improved drug delivery and more effective treatment. The delivery of lipophilic drugs such as the vinca alkaloids, and particularly vincristine and vinblastine, to tumors is significantly improved.
Inventor(s): Webb; Murray S. (Vancouver, CA), Bally; Marcel B. (Bowen Island, CA), Mayer; Lawrence D. (North Vancouver, CA)
Assignee: Inex Pharmaceuticals Corporation (Vancouver, CA)
Application Number:08/263,603
Patent Claim Types:
see list of patent claims
Composition; Dosage form; Delivery; Compound; Process; Formulation;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Talon Therap
MARQIBO KIT
vincristine sulfate
INJECTABLE, LIPOSOMAL;INTRAVENOUS202497Aug 9, 2012RXYes5,543,152<disabled>Y
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International Patent Family for Patent: 5,543,152

Country Document Number Publication Date
World Intellectual Property Organization (WIPO)9535094Dec 28, 1995
United States of America5741516Apr 21, 1998
United States of America5814335Sep 29, 1998
Portugal804159Feb 27, 2004
JapanH10501534Feb 10, 1998
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