Patent 5,453,510 protects and is included in zero NDA.
|Title:||Neuromuscular blocking agents|
|Abstract:||1R-cis,1'R-cis isomer of a 2',2'-(3,11-dioxo-4,10-dioxatridecylene)-bis(1,2,3,4-tetrahydro-6, 7-dimethoxy-2-methyl-1-veratrylisoquinolium) said, substantially free from other geometrical and optical isomers thereof. The 1R-cis,1'R-cis isomer has been found to have an advantageous combination of pharmacological properties, notably greater neuromuscular blocking potency, weaker histamine-releasing potency, and at equivalent levels of neuromuscular blockade, fewer potential adverse effects on the autonomic nervous system (sympathetic and parasympathetic blockage), in comparison with the known mixture of geometrical and optical isomers.|
|Inventor(s):||Hill; Derek A. (Dartford, GB2), Turner; Geoffrey L. (Dartford, GB2)|
|Assignee:||Burroughs Wellcome Co. (Research Triangle Park, NC)|
Patent Claim Types:|
see list of patent claims
|Compound; Composition; Use;|
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|United Kingdom||9015473||Jul 13, 1990|
|Country||Document Number||Publication Date|
|South Africa||9105468||Mar 31, 1993|
|World Intellectual Property Organization (WIPO)||9200965||Jan 23, 1992|
|United States of America||5556978||Sep 17, 1996|
|Slovakia||279907||May 07, 1999|
|Slovakia||383392||May 07, 1999|
|This preview shows a limited data set|
Subscribe for full access, or try a free trial
Export unavailable in trial.
Subscribe for complete access.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided information. There is no warranty that the information contained herein is error free. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.