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Details for Patent: 5,407,914

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Patent 5,407,914 protects SURFAXIN and is included in one NDA.

Summary for Patent: 5,407,914

Title: Pulmonary surfactant protein and related polypeptides
Abstract:The present invention discloses useful peptides and synthetic pulmonary surfactants, as well as methods of making and using same. In a preferred embodiment, a synthetic pulmonary surfactant comprises one or more pharmaceutically acceptable phospholipids admixed with a polypeptide comprising at least 10 amino acid residues and no more than about 60 amino acid residues, said polypeptide including a sequence having alternating hydrophobic and hydrophilic amino acid residue regions. In other embodiments, a surfactant peptide has an amino acid residue sequence selected from the group consisting of KLLLLKLLLLKLLLLKLLLLK, KLLLLLLLLKLLLLLLLLKLL, and KKLLLLLLLKKLLLLLLLKKL.
Inventor(s): Cochrane; Charles G. (La Jolla, CA), Revak; Susan D. (San Diego, CA)
Assignee: The Scripps Research Institute (La Jolla, CA)
Application Number:08/060,833
Patent Claim Types:
see list of patent claims
Compound; Use;
Patent PDF download available with subscription

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Discovery Labs
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International Patent Family for Patent: 5,407,914

Country Document Number Publication Date
World Intellectual Property Organization (WIPO)8906657Jul 27, 1989
World Intellectual Property Organization (WIPO)9222315Dec 23, 1992
World Intellectual Property Organization (WIPO)9849191Nov 05, 1998
United States of America5164369Nov 17, 1992
United States of America5260273Nov 09, 1993
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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