Details for Patent: 7,662,835
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Title: | Methods of treating allergic reactions using an anhydrous form of antihistaminic piperidine derivatives |
Abstract: | The present invention is related to novel processes for preparing anhydrous and hydrated forms of piperidine derivatives, polymorphs and pseudomorphs thereof of the formulas ##STR00001## which are useful as antihistamines, antiallergic agents and bronchodilators. |
Inventor(s): | McCarty; Frederick J. (Hilton Head Island, SC), Carr; Albert A. (Cincinnati, OH) |
Assignee: | Aventis Holdings, Inc. (Bridgewater, NJ) |
Filing Date: | Sep 25, 2006 |
Application Number: | 11/534,839 |
Claims: | 1. A method of treating an allergic reaction in a patient in need thereof comprising administering to said patient a solid unit dosage form comprising an effective amount of 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-.alpha.,.a- lpha.-dimethylbenzeneacetic acid hydrochloride comprising Form I anhydrous 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-.alpha.,.a- lpha.-dimethylbenzeneacetic acid hydrochloride. |