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Details for Patent: 6,207,640

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Summary for Patent: 6,207,640

Title: Treatment of partial growth hormone insensitivity syndrome
Abstract:Methods for increasing the growth rate of a human patient having partial growth hormone insensitivity syndrome, but not Laron syndrome, are described. One such method comprises administering an effective dose of growth hormone, preferably growth hormone with a native human sequence, with or without an N-terminal methionine, to the patient. The patient is characterized as having a height of less than about -2 standard deviations below normal for age and sex, a serum level of high-affinity growth hormone binding protein that is at least 2 standard deviations below normal levels, a serum level of IGF-I that is below normal mean levels, and a serum level of growth hormone that is at least normal. In another such method, the same patient population is treated with an effective amount of IGF-I, given alone or in combination with an amount of growth hormone that is effective in combination with the IGF-I.
Inventor(s): Attie; Kenneth M. (San Francisco, CA), Carlsson; Lena M. S. (Gothenburg, SE), Gesundheit; Neil (Los Altos, CA), Goddard; Audrey (San Francisco, CA)
Assignee: Genentech, Inc. (South San Francisco, CA)
Application Number:08/643,212
Patent Claim Types:
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Patent Metrics:
Source: PatentQuant.com
Field: Not categorized
Back Citations: 4th percentile
Forward Citations: 0th percentile
Patent PDF download available with subscription

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International Patent Family for Patent: 6,207,640

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Portugal914148<disabled in preview>
Portugal754048<disabled in preview>
Mexico9701916<disabled in preview>
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