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|Title:||Sphingosomes for enhanced drug delivery|
|Abstract:||Liposomal formulations having extended circulation time in vivo and increased drug retention are comprised of sphingomyelin and cholesterol and have an acidic intraliposomal pH. The formulations have enhanced stability and thus are used in methods which provide improved drug delivery and more effective treatment. The delivery of ciprofloxacin, and alkaloid drugs, particularly swainsonine, vincristine and vinblastine, is significantly improved.|
|Inventor(s):||Webb; Murray S. (Vancouver, CA), Bally; Marcel B. (Bowen Island, CA), Mayer; Lawrence D. (N. Vancouver, CA), Miller; James J. (Vancouver, CA), Tardi; Paul G. (Richmond, CA)|
|Assignee:||Inex Pharmaceuticals Corporation (CA)|
Patent Claim Types:|
see list of patent claims
|Compound; Dosage form; Process; Delivery; Formulation; Composition;|
Field: Not categorized
Back Citations: 3rd percentile
Forward Citations: 0th percentile
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|Austria||248586||<disabled in preview>|
|Australia||2709495||<disabled in preview>|
|Canada||2193502||<disabled in preview>|
| This preview shows a limited data set|
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.
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