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Last Updated: May 1, 2024

Details for Patent: 8,268,848


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Which drugs does patent 8,268,848 protect, and when does it expire?

Patent 8,268,848 protects DAYVIGO and is included in one NDA.

This patent has thirty-six patent family members in thirty-two countries.

Summary for Patent: 8,268,848
Title:Cyclopropane compound
Abstract: A cyclopropane compound represented by the following formula (A) or a pharmaceutically acceptable salt thereof has orexin receptor antagonism, and therefore has a potencial of usefulness for the treatment of sleep disorder for which orexin receptor antagonism is effective, for example, insomnia: ##STR00001## wherein Q represents --CH-- or a nitrogen atom, R.sub.1a and R.sub.1b each independently represent a C.sub.1-6 alkyl group and the like, R.sub.1c represents a hydrogen atom and the like, R.sub.2a, R.sub.2b, R.sub.2c and R.sub.2d each independently represent a hydrogen atom, a halogen atom, a C.sub.1-6 alkyl group and the like, R.sub.3a, R.sub.3b and R.sub.3c each independently represent a hydrogen atom, a halogen atom and the like, and R.sub.3d represents a hydrogen atom and the like.
Inventor(s): Terauchi; Taro (Tsukuba, JP), Takemura; Ayumi (Tsukuba, JP), Doko; Takashi (Tokyo, JP), Yoshida; Yu (Tsukuba, JP), Tanaka; Toshiaki (Tsukuba, JP), Sorimachi; Keiichi (Tsukuba, JP), Naoe; Yoshimitsu (Tsukuba, JP), Beuckmann; Carsten (Tsukuba, JP), Kazuta; Yuji (Tsukuba, JP)
Assignee: Eisai R&D Management Co., Ltd. (Tokyo, JP)
Application Number:13/237,205
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;

Drugs Protected by US Patent 8,268,848

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Eisai Inc DAYVIGO lemborexant TABLET;ORAL 212028-001 Apr 7, 2020 RX Yes No ⤷  Try a Trial ⤷  Try a Trial Y Y TREATMENT OF ADULT PATIENTS WITH INSOMNIA, CHARACTERIZED BY DIFFICULTIES WITH SLEEP ONSET AND/OR SLEEP MAINTENANCE ⤷  Try a Trial
Eisai Inc DAYVIGO lemborexant TABLET;ORAL 212028-002 Apr 7, 2020 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y TREATMENT OF ADULT PATIENTS WITH INSOMNIA, CHARACTERIZED BY DIFFICULTIES WITH SLEEP ONSET AND/OR SLEEP MAINTENANCE ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,268,848

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan2010-211629Sep 22, 2010

International Family Members for US Patent 8,268,848

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 083060 ⤷  Try a Trial
Australia 2011304285 ⤷  Try a Trial
Brazil 112013006594 ⤷  Try a Trial
Canada 2811895 ⤷  Try a Trial
Chile 2013000784 ⤷  Try a Trial
China 103153963 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.