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Last Updated: May 4, 2024

Details for Patent: 8,198,242


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Which drugs does patent 8,198,242 protect, and when does it expire?

Patent 8,198,242 protects VOXZOGO and is included in one NDA.

This patent has forty-five patent family members in twenty-four countries.

Summary for Patent: 8,198,242
Title:Variants of C-type natriuretic peptide
Abstract: The present disclosure provides variants of C-type natriuretic peptide (CNP), pharmaceutical compositions comprising CNP variants, and methods of making CNP variants. The CNP variants are useful as therapeutic agents for the treatment of diseases responsive to CNP, including but not limited to bone-related disorders, such as skeletal dysplasias (e.g., achondroplasia), and vascular smooth muscle disorders (e.g., restenosis and arteriosclerosis).
Inventor(s): Wendt; Daniel J. (Walnut Creek, CA), Long; Shinong (Milpitas, CA), Castillo; Sianna (San Francisco, CA), Price; Christopher P. (Kentfield, CA), Aoyagi-Scharber; Mika (Mill Valley, CA), Vellard; Michel C. (San Rafael, CA), Okhamafe; Augustus O. (Concord, CA)
Assignee: Biomarin Pharmaceutical Inc. (Novato, CA)
Application Number:12/784,117
Patent Claim Types:
see list of patent claims
Use; Composition; Formulation;

Drugs Protected by US Patent 8,198,242

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Biomarin Pharm VOXZOGO vosoritide POWDER;SUBCUTANEOUS 214938-001 Nov 19, 2021 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y USE TO INCREASE LINEAR GROWTH IN PEDIATRIC PATIENTS WITH ACHONDROPLASIA WHO ARE 5 YEARS OF AGE AND OLDER WITH OPEN EPIPHYSES ⤷  Try a Trial
Biomarin Pharm VOXZOGO vosoritide POWDER;SUBCUTANEOUS 214938-002 Nov 19, 2021 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y USE TO INCREASE LINEAR GROWTH IN PEDIATRIC PATIENTS WITH ACHONDROPLASIA WHO ARE 5 YEARS OF AGE AND OLDER WITH OPEN EPIPHYSES ⤷  Try a Trial
Biomarin Pharm VOXZOGO vosoritide POWDER;SUBCUTANEOUS 214938-003 Nov 19, 2021 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y USE TO INCREASE LINEAR GROWTH IN PEDIATRIC PATIENTS WITH ACHONDROPLASIA WHO ARE 5 YEARS OF AGE AND OLDER WITH OPEN EPIPHYSES ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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