Details for Patent: 11,185,497
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Which drugs does patent 11,185,497 protect, and when does it expire?
Patent 11,185,497 protects TRUDHESA and is included in one NDA.
This patent has thirteen patent family members in ten countries.
Summary for Patent: 11,185,497
| Title: | Intranasal delivery of dihydroergotamine by precision olfactory device |
| Abstract: | Methods are provided for acutely treating migraine headache with or without aura. The methods comprise administering to a subject with migraine headache an effective dose of a liquid pharmaceutical composition comprising dihydroergotamine (DHE) or a salt thereof, wherein the dose is administered by an intranasal delivery device that provides, following intranasal administration, (a) a mean peak plasma DHE concentration (C.sub.max) of at least 750 pg/ml, (b) with a mean time to C.sub.max (T.sub.max) of DHE of less than 45 minutes, and (c) a mean plasma AUC.sub.0-inf of DHE of at least 2500 pg*hr/ml. Also provided are kits for acutely treating migraine with or without aura in which a liquid pharmaceutical composition comprising DHE or DHE salt is contained within a sealed vial that is attachable to a precision intranasal olfactory delivery device packaged therewith. |
| Inventor(s): | Hoekman; John D. (Seattle, WA), Satterly; Kelsey H. (Seattle, WA), Shrewsbury; Stephen B. (Fallbrook, CA), Youmans; Scott (Bothell, WA), Fuller; Christopher (Seattle, WA) |
| Assignee: | Impel Neuropharma, Inc. (Seattle, WA) |
| Application Number: | 17/062,364 |
|
Patent Claim Types: see list of patent claims | Use; Composition; Formulation; Delivery; Device; |
Drugs Protected by US Patent 11,185,497
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Jn Bidco | TRUDHESA | dihydroergotamine mesylate | SPRAY, METERED;NASAL | 213436-001 | Sep 2, 2021 | RX | Yes | Yes | ⤷ Try a Trial | ⤷ Try a Trial | NASAL ADMINISTRATION OF DIHYDROERGOTAMINE MESYLATE BY METERED SPRAY FOR THE ACUTE TREATMENT OF MIGRAINE WITH OR WITHOUT AURA | ⤷ Try a Trial | ||||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 11,185,497
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Australia | 2019205318 | ⤷ Try a Trial | |||
| Australia | 2022202900 | ⤷ Try a Trial | |||
| Brazil | 112020013744 | ⤷ Try a Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
