CLINICAL TRIALS PROFILE FOR LEVOBUPIVACAINE HYDROCHLORIDE
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All Clinical Trials for levobupivacaine hydrochloride
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00437996 ↗ | Comparative Affect of a Continuous Epidural Infusion of Clonidine During Labour. Prospective Double Blind Randomized Trial | Completed | Hospices Civils de Lyon | Phase 3 | 2007-02-01 | Addition of clonidine to an epidural mixture of local anaesthetic and morphine improves analgesia and reduces the frequency of motor blockade during epidural analgesia. several side effects are possible mostly somnolence and hypotension. Association of continuous clonidine infusion with low concentrations of levobupivacaïne and sufentanil was not studied during labour. The objective of this study is to compare the effectiveness and the side effects of a PCEA with levobupivacaïne 0,0625 % and sufentanil 0.25 microg.ml-1, without addition of clonidine, and with addition of clonidine at a concentrations of 2 microg.ml-1. |
| NCT00523289 ↗ | Cardiovascular Safety Research: Bupivacaine With Vasoconstrictor Versus Ropivacaine in Brachial Plexus Block | Unknown status | Cristália Produtos Químicos Farmacêuticos Ltda. | Phase 4 | 2007-10-01 | The purpose of this study is to determine if bupivacaine (75% levobupivacaine plus 25% racemic bupivacaine) with vasoconstrictor is effective and safety as ropivacaine in brachial plexus block for orthopedic surgery. |
| NCT00523289 ↗ | Cardiovascular Safety Research: Bupivacaine With Vasoconstrictor Versus Ropivacaine in Brachial Plexus Block | Unknown status | University of Sao Paulo | Phase 4 | 2007-10-01 | The purpose of this study is to determine if bupivacaine (75% levobupivacaine plus 25% racemic bupivacaine) with vasoconstrictor is effective and safety as ropivacaine in brachial plexus block for orthopedic surgery. |
| NCT00552864 ↗ | Comparison of Ropivacaine and Levobupivacaine in High Thoracic Epidural Anesthesia | Completed | Centro Cardiologico Monzino | Phase 4 | 2003-01-01 | In High Thoracic Epidural Anesthesia (HTEA) the use of a local anesthetic (LA) with low cardiac toxicity is crucial as myocardial contractility is often already seriously impaired. The aim of this study is to compare the efficacy, doses and side effects of ropivacaine and levobupivacaine in patients submitted to coronary artery bypass graft with HTEA and general anesthesia. The primary end point is the amount of LA drug required to maintain a VAS < 4 when coughing in the first 24 postoperative hours. |
| NCT00621907 ↗ | Study : LEVOBUPIVACAINE Versus Placebo | Completed | Centre Hospitalier Universitaire de Saint Etienne | Phase 3 | 2008-03-01 | The locoregional anaesthesia is increasingly important in surgical practice, often allowing to simplify per- and post-operative analgesia. caesarian occurs in 20 % of delivery leading to a longer hospitalization because of the pain resulting from the surgery. The Levobupivacaïne (Chirocaïne) administered through catheters placed in the caesarean scars, showed its efficiency in post-operative analgesia. Method : realization of a double blind prospective randomized study, control versus placebo Purpose : to show that the local administration of a unique dose of analgesia reduce the post-operative pain with a little or non-invasive technique |
| NCT00682344 ↗ | Pharmacokinetic of levobupivacaïne After Sciatic Nerve Block in Children | Terminated | Assistance Publique Hopitaux De Marseille | Phase 3 | 2008-01-01 | Levobupivacaïne (Chirocaine®) is a new local anaesthetic recently marketed in France. The goal of this prospective work is to study the pharmacokinetic aspect of this drug after injection around the sciatic nerve (subgluteal way). |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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