The Application of Docozine Combined With Sufentanil for Awake Tracheal Intubation
Completed
The First Affiliated Hospital of Anhui Medical University
Phase 4
2016-03-01
Mortality associated with difficult airway in anesthesia is up to 30%. So, it is urgent to
find a safe and effective method for intubation. Awake tracheal intubation which is used to
retain spontaneous breathing is one of the important measures to ensure the safety of the
patients with difficult airway in anesthesia.
Sufentanil is used to provide good analgesia and can effectively inhibit the reaction of
awake tracheal intubation, however, the outstanding problem is serious respiratory depression
after intravenous sufentanil injection. Few study showed that dezocine is a kappa opioid
antagonist related to mild respiratory depression and can prevents sufentanil-induced cough
during general anesthesia induction.It is necessary to carry out large-scale, multi-center,
randomized, controlled clinical study to determine whether dezocine prevents
sufentanil-induced respiratory depression and whether dezocine combined sufentanil is a safe
and effective method for awake tracheal intubation.
The Effects of Dezocine Pretreatment on Dexamethasone Induced Perineal Irritation
Completed
General Hospital of Ningxia Medical University
N/A
2016-05-01
The purpose of this study is to investigate the efficacy of dezocine pretreatment on
dexamethasone 21-phosphate induced perineal irritation (include pian and pruritus).
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.