CLINICAL TRIALS PROFILE FOR LOMOTIL
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All Clinical Trials for LOMOTIL
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT00583323 ↗ | Diphenoxylate / Atropine to Decrease FDG Activity During F-18 FDG PET | Completed | Mayo Clinic | Phase 3 | 2003-02-01 | 2-[18F]-fluoro-2-deoxyD-glucose positron emission tomography (FDG PET) has proven to be a valuable clinical tool for the staging and surveillance of lymphoma.1-6 Occasionally, lymph nodes in the mesentery and retroperitoneum can be difficult to distinguish from normal bowel activity on PET scans despite three-plane and cine maximal image projection (MIP) imaging. This uncertainty limits the clinical usefulness of PET in some cases of lymphoma.7-8 In addition, bowel activity can also hinder interpretation of PET scans in other types of solid tumors including melanoma and colorectal cancer.6,9,10 Our goal is to determine how well diphenoxylate/atropine 5mg/0.05mg (Lomotil) decreases bowel activity and how this decrease impacts clinical decision-making, specifically for lymphoma staging and surveillance. This is a prospective, randomized, double-blinded study involving 60 patients undergoing PET scans for newly diagnosed or recurrent, untreated lymphoma. |
NCT00591357 ↗ | Efficacy of Loperamide for C. Difficile Colitis and Other Diarrheal Diseases Associated With Antibiotic Therapy | Suspended | Michael E. DeBakey VA Medical Center | Phase 4 | 2007-10-01 | To determine whether symptomatic treatment of the diarrhea in CDAD reduces morbidity and mortality of this serious nosocomial infection in patients who have antibiotic-associated diarrhea. Both C. diff positive and negative patients will be included. |
NCT00591357 ↗ | Efficacy of Loperamide for C. Difficile Colitis and Other Diarrheal Diseases Associated With Antibiotic Therapy | Suspended | VA Medical Center, Houston | Phase 4 | 2007-10-01 | To determine whether symptomatic treatment of the diarrhea in CDAD reduces morbidity and mortality of this serious nosocomial infection in patients who have antibiotic-associated diarrhea. Both C. diff positive and negative patients will be included. |
NCT02018653 ↗ | CASAD for Severe Diarrhea in the Emergency Department | Terminated | Salient Pharmaceuticals Incorporated | N/A | 2013-12-01 | The goal of this clinical research study is to learn if calcium alumina-silicate (CASAD) can help to stop your diarrhea. Researchers also want to know if this drug can help decrease the duration of your diarrhea. In this study, CASAD will be compared to a placebo. A placebo is not a drug. It looks like the study drug but it is not designed to treat any disease or illness. It is designed in this study to be compared with the study drug to learn if the study drug has any real effect. |
NCT02018653 ↗ | CASAD for Severe Diarrhea in the Emergency Department | Terminated | M.D. Anderson Cancer Center | N/A | 2013-12-01 | The goal of this clinical research study is to learn if calcium alumina-silicate (CASAD) can help to stop your diarrhea. Researchers also want to know if this drug can help decrease the duration of your diarrhea. In this study, CASAD will be compared to a placebo. A placebo is not a drug. It looks like the study drug but it is not designed to treat any disease or illness. It is designed in this study to be compared with the study drug to learn if the study drug has any real effect. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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