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Listing of Drug Product Information by Patent Expiration - 2015

Range: 1 - 5

Applicant Tradename Generic Name NDA Approval Date Type Patent Number Patent Expiration Patented / Exclusive Use Helsinn Hlthcare ALOXI palonosetron hydrochloride 021372 Jul 25, 2003 RX 5,202,333 Apr 13, 2015 PREVENTION OF CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING Glaxo Grp Ltd FLOVENT HFA fluticasone propionate 021433 May 14, 2004 RX 6,253,762 Apr 14, 2015 METHOD FOR THE TREATMENT OF A RESPIRATORY DISORDER, E.G. ASTHMA, COMPRISING ADMINISTERING AN EFFECTIVE AMOUNT OF AN AEROSOL COMPOSITION TO A PATIENT FROM A METERED DOSE INHALER SYSTEM AS CLAIMED IN US PATENT NO. 6253762 Glaxo Grp Ltd FLOVENT HFA fluticasone propionate 021433 May 14, 2004 RX 6,546,928 Apr 14, 2015 METHOD FOR THE TREATMENT OF A RESPIRATORY DISORDER, E.G. ASTHMA, COMPRISING ADMINISTERING TO A PATIENT BY INHALATION, A METERED AEROSOL DOSE OF A DRUG FORMULATION FROM THE METERED DOSE INHALER SYSTEM CLAIMED IN US 6546928 Glaxosmithkline ADVAIR HFA fluticasone propionate; salmeterol xinafoate 021254 Jun 8, 2006 RX 6,143,277 Apr 14, 2015 INDICATED FOR THE LONG-TERM, TWICE-DAILY MAINTENANCE TREATMENT OF ASTHMA IN PATIENTS 12 YEARS OF AGE OR OLDER Glaxosmithkline ADVAIR HFA fluticasone propionate; salmeterol xinafoate 021254 Jun 8, 2006 RX 6,253,762 Apr 14, 2015 INDICATED FOR THE LONG-TERM, TWICE-DAILY MAINTENANCE TREATMENT OF ASTHMA IN PATIENTS 12 YEARS OF AGE OR OLDER

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