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TIMOPTIC Drug Profile

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When do Timoptic patents expire, and when can generic versions of Timoptic launch?

Timoptic is a drug marketed by Aton and Valeant Pharms Llc and is included in three NDAs.

The generic ingredient in TIMOPTIC is timolol maleate. There are fifteen drug master file entries for this compound. Eighteen suppliers are listed for this compound. Additional details are available on the timolol maleate profile page.

Summary for TIMOPTIC

US Patents:	0
Applicants:	2
NDAs:	3
Suppliers / Packagers:	2
Bulk Api Vendors:	25
Clinical Trials:	16
Patent Applications:	4,330
Formulation / Manufacturing:	see details
Drug Prices:	see details
DailyMed Link:	TIMOPTIC at DailyMed

Pharmacology for TIMOPTIC

Drug Class	beta-Adrenergic Blocker
Mechanism of Action	Adrenergic beta-Antagonists

Synonyms for TIMOPTIC

(-)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole

(-)-Timolol

(2S)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol

(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

(2S)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol

(2S)-1-[(1,1-dimethylethyl)amino]-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

(2S)-3-[(tert-butyl)amino]-1-(4-morpholin-4-yl(1,2,5-thiadiazol-3-yl)oxy)propa n-2-ol

(S)-1-(1,1-(Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol

(S)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol

(S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

(S)-1-tert-Butylamino-3-(4-morpholin-4-yl-[1,2,5]thiadiazol-3-yloxy)-propan-2-ol

(S)-timolol

(S)-timolol (anhydrous)

1-(tert-butylamino)-3-[4-(1,4-oxazinan-4-yl)-1,2,5-thiadiazol-3-yloxy]-(2S)-propan-2-ol

131628-37-0

194288-09-0

2-Propanol, 1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-, (2S)-

2-Propanol, 1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-, (S)-

2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)-

2-Propanol,1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-,(2S)-

26839-75-8

26921-17-5 (maleate (1:1) salt)

5JKY92S7BR

839T758

AB00513729

AB00513729-17

AC1L1PYN

AC1Q59QM

AKOS015969764

API0004422

Apo-Timol

Apo-Timol (TN)

Apo-Timop

Apo-Timop (TN)

Aquanil

ARONIS24479

arutimol

BBC/645

BDBM50292219

Betim

Betimol

Betimol (TN)

BIDD:GT0073

BLJRIMJGRPQVNF-JTQLQIEISA-N

Blocadren

Blocadren (TN)

BPBio1_001008

BRD-K08806317-050-03-6

BSPBio_000916

C-19486

C07141

CAS-26839-75-8

CAS-26921-17-5

CC-35068

CHEBI:9599

CHEMBL499

CTK4F8602

D05UVD

D08600

DB00373

DSSTox_CID_3674

DSSTox_GSID_23674

DSSTox_RID_77140

DTXSID4023674

EINECS 248-032-6

FT-0630529

Gen-Timolol (TN)

GTPL565

HE061310

HE330337

HMS2089I11

HMS3259C20

HSDB 6533

Istalol

Istalol (TN)

L-714,465

L-Timolol

Lopac-T-6394

Lopac0_001189

LS-122231

MK-950

MolPort-006-125-123

NC00592

NCGC00016038-01

NCGC00016038-02

NCGC00016798-01

NCGC00016798-02

NCGC00016798-03

NCGC00016798-05

NCGC00016798-06

NCGC00016798-07

NCGC00016798-08

NCGC00016798-09

NCGC00016798-11

NCGC00022033-02

NCGC00022033-04

NCGC00022033-05

Novo-Timol

Nu-Timolol

Nu-Timolol (TN)

Oprea1_640981

Optimol

Phoxal-timolol

Phoxal-timolol (TN)

PMS-Timolol (TN)

Prestwick0_000948

Prestwick1_000948

Prestwick2_000948

Prestwick3_000948

Proflax

S-(-)-3-(3-tert-Butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole

S(-)-Timolol maleate

SCHEMBL4912

SPBio_003075

ST072193

Temserin

Tenopt

TIM

Tim-AK

Tim-AK (TN)

Timacar

Timacor

timolol

Timolol (INN)

Timolol (TN)

Timolol [USAN:INN]

Timolol [USAN]

Timolol anhydrous

Timolol GFS

Timolol maleate

Timolol Maleate, (1:1) Salt

Timololo

Timololum

Timololum [INN-Latin]

Timopic

Timoptic (TN)

Timoptic OcuDose

Timoptic OcuDose. (TN)

Timoptic-XE

Timoptic-XE (TN)

Timoptol

Tocris-0649

Tox21_110614

Tox21_110614_1

UNII-5JKY92S7BR

W-107148

ZINC2176

US Patents and Regulatory Information for TIMOPTIC

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Aton	TIMOPTIC	timolol maleate	SOLUTION/DROPS;OPHTHALMIC	018086-001	Approved Prior to Jan 1, 1982	AT	RX	Yes	No
Aton	TIMOPTIC IN OCUDOSE	timolol maleate	SOLUTION/DROPS;OPHTHALMIC	019463-002	Nov 5, 1986		RX	Yes	Yes
Aton	TIMOPTIC	timolol maleate	SOLUTION/DROPS;OPHTHALMIC	018086-002	Approved Prior to Jan 1, 1982	AT1	RX	Yes	No
Aton	TIMOPTIC IN OCUDOSE	timolol maleate	SOLUTION/DROPS;OPHTHALMIC	019463-001	Nov 5, 1986		RX	Yes	Yes

Expired US Patents for TIMOPTIC

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration
Aton	TIMOPTIC	timolol maleate	SOLUTION/DROPS;OPHTHALMIC	018086-002	Approved Prior to Jan 1, 1982
Aton	TIMOPTIC	timolol maleate	SOLUTION/DROPS;OPHTHALMIC	018086-002	Approved Prior to Jan 1, 1982
Aton	TIMOPTIC	timolol maleate	SOLUTION/DROPS;OPHTHALMIC	018086-001	Approved Prior to Jan 1, 1982
Aton	TIMOPTIC	timolol maleate	SOLUTION/DROPS;OPHTHALMIC	018086-001	Approved Prior to Jan 1, 1982