DrugPatentWatch Database Preview
RIOMET Drug Profile
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Which patents cover Riomet, and what generic alternatives are available?
This drug has eighteen patent family members in eighteen countries.
The generic ingredient in RIOMET is metformin hydrochloride. There are forty-eight drug master file entries for this compound. One hundred and twelve suppliers are listed for this compound. Additional details are available on the metformin hydrochloride profile page.
Summary for RIOMET
| International Patents: | 18 |
| US Patents: | 1 |
| Applicants: | 1 |
| NDAs: | 1 |
| Suppliers / Packagers: | 1 |
| Bulk Api Vendors: | 105 |
| Clinical Trials: | 28 |
| Patent Applications: | 38 |
| Formulation / Manufacturing: | see details |
| DailyMed Link: | RIOMET at DailyMed |
Pharmacology for RIOMET
| Ingredient-type | Biguanides |
| Drug Class | Biguanide |
Medical Subject Heading (MeSH) Categories for RIOMET
Synonyms for RIOMET
| (E)-2-carbamimidoyl-1,1-dimethylguanidine hydrochloride |
| 1-dimethylbiguanide hydrochloride |
| 1,1-Dimethylbiguanide hydrochloride |
| 1,1-Dimethylbiguanide hydrochloride, 97% |
| 1,1-Dimethylbiguanide monohydrochloride |
| 1,1-Dimethylbiguanide, Hydrochloride |
| 1115-70-4 |
| 144377-16-2 |
| 15537-72-1 |
| 3-(diaminomethylene)-1,1-dimethyl-guanidine hydrochloride |
| 3-(diaminomethylidene)-1,1-dimethylguanidine hydrochloride |
| 3-carbamimidoyl-1,1-dimethylguanidine;hydrochloride |
| 56258-19-6 |
| 786Z46389E |
| AB0004717 |
| AB1009370 |
| AC-2075 |
| AC1L23D5 |
| ACMC-20ap7s |
| AI3-51264 |
| AK163172 |
| AKOS015894259 |
| AN-8747 |
| API0003318 |
| Apo-Metformin |
| AX8041182 |
| BB_SC-5098 |
| BC206669 |
| Benofomin |
| BG0401 |
| BIGUANIDE, 1,1-DIMETHYL-, HYDROCHLORIDE |
| Biguanide, 1,1-dimethyl-, monohydrochloride |
| Biguanide, 1,1-dimethyl-, monohydrochloride (8CI) |
| Biguanide,1-dimethyl-, monohydrochloride |
| Biocos |
| BP-12830 |
| C4H11N5.HCl |
| C4H12ClN5 |
| CAS-1115-70-4 |
| CCG-208004 |
| CHEBI:6802 |
| CHEMBL1703 |
| Cidophage |
| CS-1851 |
| CTK8C6229 |
| D 15095 |
| D.B.I |
| D.B.I. |
| D00944 |
| Dabex |
| DB-018697 |
| Denkaform |
| Dextin |
| Diabefagos |
| Diaberit |
| Diabesin |
| Diabetex |
| Diabetmin |
| Diaformin |
| Diamin |
| Diaphage |
| Diformin |
| Diformin Retard |
| Dimethylbiguanide hydrochloride |
| DMBG hydrochloride |
| DMGG hydrochloride |
| DSSTox_CID_17246 |
| DSSTox_GSID_37246 |
| DSSTox_RID_79314 |
| DTXSID9037246 |
| EC 214-230-6 |
| EINECS 214-230-6 |
| F2173-0894 |
| Fornidd |
| Fortamet |
| FT-0628265 |
| Geamet |
| Glibomet |
| Glucofago |
| Glucoform |
| Glucoliz |
| Glucomet |
| Glucomine |
| Gluconil |
| Glucophage |
| Glucophage (TN) |
| Glucophage 850 |
| Glucophage Forte |
| Glucophage Retard |
| Glucophage XR |
| Glucophage-Mite |
| Gluformin |
| Glupermin |
| Glyciphage |
| Glycoran |
| Glyformin |
| GP2747 |
| Haurymellin hydrochloride |
| HMS1568A09 |
| HMS1922H14 |
| HSDB 7080 |
| HY-17471A |
| I05-0228 |
| I14-7880 |
| I506 |
| Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride |
| Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride (9CI) |
| Imidodicarbonimidic diamide,N-dimethyl-, monohydrochloride |
| Islotin retard |
| J10020 |
| J10377 |
| Jsp000870 |
| KS-000006B5 |
| KS-1272 |
| KSC926E2T |
| LA 6023 |
| LA 6063 |
| LS-43900 |
| M-2922 |
| M2009 |
| MCULE-9784059944 |
| Meglucon |
| Meguan |
| Mescorit |
| Metbay |
| Metforal |
| Metformin (hydrochloride) |
| Metformin HCL |
| Metformin HCl ER |
| Metformin HCl(Glucophage) |
| Metformin hydrochloride |
| Metformin hydrochloride (Glucophage) |
| Metformin hydrochloride (JP17/USP) |
| Metformin hydrochloride [USAN:USP:JAN] |
| Metformin hydrochloride [USAN] |
| Metformin Hydrochloride 1.0 mg/ml in Methanol (as free base) |
| Metformin hydrochloride, British Pharmacopoeia (BP) Reference Standard |
| Metformin hydrochloride, European Pharmacopoeia (EP) Reference Standard |
| Metformin hydrochloride, pharmaceutical secondary standard; traceable to USP and PhEur |
| Metformin hydrochloride, United States Pharmacopeia (USP) Reference Standard |
| Metformin monohydrochloride |
| Metiguanide monohydrochloride |
| Metolmin |
| Metomin |
| MFCD00012582 |
| MLS000028493 |
| MLS002222221 |
| MolPort-000-771-764 |
| MolPort-039-227-817 |
| N-[amino(dimethylamino)methylidene]guanidine hydrochloride |
| N,N-Dimethylbiguanide hydrochloride |
| N,N-dimethylimidodicarbonimidic diamide hydrochloride |
| N,N-Dimethylimidodicarbonimidic diamine |
| N',N'-dimethylbiguanide hydrochloride |
| N1,N1-Dimethylbiguanide hydrochloride |
| NCGC00016564-01 |
| NCGC00016564-06 |
| NCGC00095185-01 |
| NCGC00095185-02 |
| Novo-Metformin |
| NSC 91485 |
| NSC-759262 |
| NSC-91485 |
| NSC759262 |
| NSC91485 |
| OETHQSJEHLVLGH-UHFFFAOYSA-N |
| OR145246 |
| Pharmakon1600-01505814 |
| Prestwick_519 |
| Q-201360 |
| Risidon |
| RP22848 |
| RTR-002281 |
| s1950 |
| SC-17468 |
| SCHEMBL10325580 |
| SCHEMBL22977 |
| Siamformet |
| SMR000058277 |
| SPECTRUM1505814 |
| ST24048701 |
| SY001217 |
| Thiabet |
| TL8000340 |
| Tox21_110498 |
| Tox21_110498_1 |
| TR-002281 |
| TRA0069243 |
| UNII-786Z46389E |
| Walaphage |
| Z2244578658 |
US Patents and Regulatory Information for RIOMET
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sun Pharm Inds Ltd | RIOMET | metformin hydrochloride | SOLUTION;ORAL | 021591-001 | Sep 11, 2003 | RX | Yes | Yes | ➤ Sign Up | ➤ Sign Up | Y | ➤ Sign Up | |||
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Exclusivity Expiration |
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Paragraph IV (Patent) Challenges for RIOMET
| Drugname | Dosage | Strength | RLD | Submissiondate |
|---|---|---|---|---|
| ➤ Subscribe | Oral Solution | 500 mg/5 mL | ➤ Subscribe | 2018-02-02 |
Non-Orange Book US Patents for RIOMET
For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.
The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.
| Patent No. | Title | Estimated Patent Expiration |
|---|---|---|
| 6,559,187 | Liquid formulation of metformin | ➤ Sign Up |
| Patent No. | Title | Estimated Patent Expiration |
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International Patents for RIOMET
| Country | Document Number | Estimated Expiration |
|---|---|---|
| Iceland | 6709 | ➤ Sign Up |
| Canada | 2416767 | ➤ Sign Up |
| Japan | 2004505913 | ➤ Sign Up |
| Yugoslavia | 8803 | ➤ Sign Up |
| Country | Document Number | Estimated Expiration |
Supplementary Protection Certificates for RIOMET
| Supplementary Protection Certificate | SPC Country | SPC Expiration | SPC Description |
|---|---|---|---|
| 00357 | Netherlands | ➤ Sign Up | PRODUCT NAME: SITAGLIPTINE, DESGEWENST IN DE VORM VAN EEN FARMACEUTISCH AANVA ARDBAAR ZOUT, IN HET BIJZONDER HET MONOFOSFAAT, EN METFORMINE DESGEWENST IN DE VORM VAN EEN FARMACEUTISCH AANVAARDBAAR ZOUT, IN HET BIJZONDER HET HYDROCHLORIDE; REGISTRATION NO/DATE: EU/1/08/455/001-014 20080716 |
| 2014026 | Lithuania | ➤ Sign Up | PRODUCT NAME: DAPAGLIFOZINUM + METFORMINUM; REGISTRATION NO/DATE: EU/1/13/900 20140116 |
| C0028 | France | ➤ Sign Up | PRODUCT NAME: ASSOCIATION COMPRENANT LA SAXAGLIPTINE OU UN DE SES SELS ET LA METFORMINE OU UN DE SES SELS, Y COMPRIS L'ASSOCIATION CHLORHYDRATE DE SAXAGLIPTINE ET CHLORHYDRATE DE METFORMINE; REGISTRATION NO/DATE: EU/1/11/731/001 20111124 |
| C/GB08/040 | United Kingdom | ➤ Sign Up | PRODUCT NAME: SITAGLIPTIN OPTIONALLY IN THE FORM OF A PHARMACEUTICALLY ACCEPTABLE SALT, IN PARTICULAR THE MONOPHOSPHATE, PLUS METFORMIN OPTIONALLY IN THE FORM OF A PHARMACEUTICALLY ACCEPTABLE SALT, IN PARTICULAR THE HYDROCHLORIDE.; REGISTERED: CH 58450 01-03 20080408; UK EU/1/08/455/001 20080716; UK EU/1/08/455/002 20080716; UK EU/1/08/455/003 20080716; UK EU/1/08/455/004 20080716; UK EU/1/08/455/005 20080716; UK EU/1/08/455/006 20080716; UK EU/1/08/455/007 20080716; UK EU/1/08/455/008 20080716; UK EU/1/08/455/009 20080716; UK EU/1/08/455/010 20080716; UK EU/1/08/455/011 20080716; UK EU/1/08/455/012 20080716; UK EU/1/08/455/013 20080716; UK EU/1/08/455/014 20080716 |
| Supplementary Protection Certificate | SPC Country | SPC Expiration | SPC Description |
