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CONZIP Drug Profile

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When do Conzip patents expire, and what generic alternatives are available?

Conzip is a drug marketed by Cipher Pharms Inc and is included in one NDA. There is one patent protecting this drug.

This drug has three patent family members in three countries.

The generic ingredient in CONZIP is tramadol hydrochloride. There are thirty-six drug master file entries for this compound. Sixty-five suppliers are listed for this compound. Additional details are available on the tramadol hydrochloride profile page.

Summary for CONZIP

International Patents:	3
US Patents:	1
Applicants:	1
NDAs:	1
Suppliers / Packagers:	14
Bulk Api Vendors:	68
Patent Applications:	1,359
Formulation / Manufacturing:	see details
Drug Prices:	see details
DailyMed Link:	CONZIP at DailyMed

Pharmacology for CONZIP

Drug Class	Opioid Agonist
Mechanism of Action	Full Opioid Agonists

Medical Subject Heading (MeSH) Categories for CONZIP

Analgesics, Opioid

Narcotics

Synonyms for CONZIP

( inverted exclamation markA)-cis-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride

(+-)-cis-2-((Dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride

(+-)-cis-2-((Dimethylamino)methyl)-1-(m-methoxyphenyl)cyclohexanol hydrochloride

(+)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride

(+)-Tramadol Hydrochloride

(+)-Tramadol-d6 Hydrochloride

(+)-Tramadol,hydrochloride

(+)-trans-Tramadol Hydrochloride

(1R-cis)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol Hydrochloride

(1R,2R)-2-((Dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride

(1R,2R)-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)-cyclohexanol hydrochloride

(1R,2R)-2-(dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexan-1-ol hydrochloride

(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol;hydrochloride

(1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol Hydrochloride

(1R,2R)-rel-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol Hydrochloride

(R,R)-tramadol hydrochloride

[(1R,2R)-2-hydroxy-2-(3-methoxyphenyl)cyclohexyl]-N,N-dimethylmethanaminium chloride

1109217-84-6

148229-78-1

194602-08-9

204T882

22203-92-5

22204-88-2

36282-47-0

53611-16-8

AB1009456

AC-796

AC1L1Y7D

Adolanta

AK153206

AK402423

AKOS015907739

Amadol

AN-15516

API0000067

API0004461

AX8154449

BC202864

Bellatram

C16H25NO2.HCl

CCG-101135

Cemadol

CG 315

CG-315E

CHEBI:75733

CHEMBL1200336

cis-(+-)-E 383 hydrochloride

cis-(+/-)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol Hydrochloride

cis-(1)-2-((Dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexan-1-ol hydrochloride

cis-Tramadol hydrochloride

cis-Tramadol hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material

Contramal

CPD000449308

CS-2770

CTK8G3518

Cyclohexanol, 2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-, hydrochloride, (1R,2R)-rel-

Cyclohexanol, 2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-, hydrochloride, cis-

Cyclohexanol, 2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-, hydrochloride, cis-( -)-

Cyclohexanol, 2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-, hydrochloride, cis-(+-)-

Cyclohexanol, 2-((dimethylamino)methyl)-1-(m-methoxyphenyl)-, hydrochloride, cis-(+-)-

D01355

Dolana

DTXSID7023691

E 382

EINECS 252-950-2

EINECS 258-662-3

FT-0638197

FT-0675345

FT-0675347

HSDB 7047

HY-B0582A

I14-2711

Ira-Tramadol

Jsp004511

K-8120

KS-1124

LS-174590

LS-191406

LS-57120

Mabron

MCULE-3504250719

Melanate

MFCD00798507

MLS000758218

MLS001424208

NC00385

NIH 10969

Omnidol

Poltram

PPKXEPBICJTCRU-XMZRARIVSA-N

Q-201847

Radol

RT-015840

Rybix

Rybix ODT

SAM001246847

SAM001247044

SBB067292

SC-77562

SCHEMBL41748

SMR000449308

Synapryn

Tadol

TL8001847

Trabar

Tradol-Puren

Tradonal

Tramadex

Tramadol HCl

Tramadol HCl; (+/-)cis-2-((Dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanolhydrochloride

tramadol hydrochloride

Tramadol hydrochloride (JAN/USAN)

Tramadol hydrochloride [USAN:JAN]

Tramadol hydrochloride [USAN:USP:JAN]

Tramadol Hydrochloride 1.0 mg/ml in Methanol (as free base)

tramadol hydrochloride tablets

Tramadol hydrochloride, >=98% (HPLC), solid

Tramadol hydrochloride, >=99.0% (HPLC)

Tramadol hydrochloride, British Pharmacopoeia (BP) Reference Standard

Tramadol hydrochloride, European Pharmacopoeia (EP) Reference Standard

Tramadol hydrochloride, United States Pharmacopeia (USP) Reference Standard

TRAMADOL/HCL

tramadole hydrochloride

TRAMADOLHydrochloride

Tramagetic

Tramal

Tramal Retard

Tramazac

Tramed

Tramol

Tridol

Tridural

U 26,225A

U-26,225A

U-26225A

Ultram (TN)

Ultram ER

UNII-9N7R477WCK component PPKXEPBICJTCRU-XMZRARIVSA-N

Viotra

W0081

Zumatran

Zydol

Zydol hydrochloride

Zydol XL 150

US Patents and Regulatory Information for CONZIP

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Cipher Pharms Inc	CONZIP	tramadol hydrochloride	CAPSULE, EXTENDED RELEASE;ORAL	022370-001	May 7, 2010		RX	Yes	Yes			Y
Cipher Pharms Inc	CONZIP	tramadol hydrochloride	CAPSULE, EXTENDED RELEASE;ORAL	022370-003	May 7, 2010		RX	Yes	No			Y
Cipher Pharms Inc	CONZIP	tramadol hydrochloride	CAPSULE, EXTENDED RELEASE;ORAL	022370-004	Aug 1, 2011		RX	Yes	No
Cipher Pharms Inc	CONZIP	tramadol hydrochloride	CAPSULE, EXTENDED RELEASE;ORAL	022370-002	May 7, 2010		RX	Yes	No			Y

International Patents for CONZIP

Country	Document Number	Estimated Expiration
Australia	2002337967
Canada	2495463
World Intellectual Property Organization (WIPO)	2004110410

Supplementary Protection Certificates for CONZIP

Supplementary Protection Certificate	SPC Country	SPC Expiration	SPC Description
C/GB04/012	United Kingdom		PRODUCT NAME: TRAMADOL HYDROCHLORIDE, PARACETAMOL; REGISTERED: FR NL 25970 20020405; UK PL 00242/0384 20030925
00152	Netherlands		PRODUCT NAME: TRAMADOLI HYDROCHLORIDUM EN PARACETAMOLUM; NAT. REGISTRATION NO/DATE: RVG 28113 20030115; FIRST REGISTRATION: 359 228-3 2002050405