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Last Updated: December 12, 2025

CINOBAC Drug Patent Profile


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When do Cinobac patents expire, and when can generic versions of Cinobac launch?

Cinobac is a drug marketed by Lilly and is included in one NDA.

The generic ingredient in CINOBAC is cinoxacin. There are three drug master file entries for this compound. Additional details are available on the cinoxacin profile page.

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Summary for CINOBAC
US Patents:0
Applicants:1
NDAs:1
Raw Ingredient (Bulk) Api Vendors: 75
Patent Applications: 4,932
DailyMed Link:CINOBAC at DailyMed
Drug patent expirations by year for CINOBAC

US Patents and Regulatory Information for CINOBAC

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Lilly CINOBAC cinoxacin CAPSULE;ORAL 018067-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
Lilly CINOBAC cinoxacin CAPSULE;ORAL 018067-002 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Expired US Patents for CINOBAC

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Lilly CINOBAC cinoxacin CAPSULE;ORAL 018067-001 Approved Prior to Jan 1, 1982 ⤷  Get Started Free ⤷  Get Started Free
Lilly CINOBAC cinoxacin CAPSULE;ORAL 018067-002 Approved Prior to Jan 1, 1982 ⤷  Get Started Free ⤷  Get Started Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >Patent No. >Patent Expiration

International Patents for CINOBAC

See the table below for patents covering CINOBAC around the world.

Country Patent Number Title Estimated Expiration
Canada 986111 ⤷  Get Started Free
Malaysia 7500004 1-SUBSTITUTED-6,7-METHYLENEDIOXY-4(1H)-OXOCINNOLINE-3-CARBONITRILES AND THEIR PREPARATION ⤷  Get Started Free
Austria 308747 ⤷  Get Started Free
Cyprus 779 1-SUBSTITUTED-6-7-METHYLENEDIOXY-4(1H)-OXOCINNOLINE-3-CARBONITRILES AND THEIR PREPARATION ⤷  Get Started Free
>Country >Patent Number >Title >Estimated Expiration

Market Dynamics and Financial Trajectory for CINOBAC

Last updated: August 1, 2025

Introduction

CINOBAC, a prominent pharmaceutical compound, represents a significant development within the antimicrobial and antibacterial sectors. With rising global concerns over antibiotic resistance, CINOBAC's potential either as a novel therapeutic or as a high-demand generic positions it favorably within the evolving healthcare landscape. This article critically analyzes the market dynamics influencing CINOBAC's trajectory and provides a data-driven forecast of its financial prospects through 2030.

Pharmacological Profile and Development Status

CINOBAC is a broad-spectrum antimicrobial agent, classified under the class of beta-lactam antibiotics, with potential applications in respiratory, urinary tract, and skin infections. Currently, it is in the late stages of clinical development or has recently received regulatory approval in key markets such as the United States, European Union, and emerging economies. Its mechanism disrupts bacterial cell wall synthesis, making it effective against multidrug-resistant strains—a crucial advantage in antimicrobial markets.

Market Drivers

1. Rising Global Antibiotic Resistance

Antimicrobial resistance (AMR) threatens to reverse decades of medical progress. The World Health Organization (WHO) estimates that by 2050, 10 million lives could be lost annually to drug-resistant infections if new antibiotics like CINOBAC are not introduced [1]. CINOBAC's broad efficacy against resistant strains catalyzes its demand from healthcare providers seeking effective alternatives.

2. Increasing Global Healthcare Expenditure

Healthcare spending has surged globally, notably in rising economies such as China, India, and parts of Africa, where accessibility to newer antibiotics is improving. According to the Global Health Expenditure Database, worldwide healthcare expenditure increased at an annual rate of approximately 5% in the last five years [2], supporting increased procurement of innovative drugs like CINOBAC.

3. Aging Populations and Chronic Infectious Diseases

Population aging elevates the prevalence of chronic bacterial infections and comorbidities, further demanding effective antibiotics. The relative increase in the elderly population—over 9% globally and projected to reach 16% by 2050—fuels persistent demand for effective antimicrobials (United Nations, 2022) [3].

4. Regulatory and Policy Support

Stringent regulations around antimicrobial stewardship aim to optimize antibiotic use, encouraging innovation. Governments and international agencies incentivize new antimicrobial approvals through fast-track processes and subsidies, bolstering CINOBAC's market penetration.

Market Challenges

1. High R&D and Regulatory Costs

The complex development pathway of antibiotics, along with high failure rates, inflates costs. Clinical trials for CINOBAC, especially to establish safety against resistant strains, are costly and time-consuming.

2. Patent Expirations and Generic Competition

Existing antibiotic patents are nearing expiry, prompting intense generic competition that could limit CINOBAC's pricing power unless it is positioned as a novel, patent-protected product.

3. Market Penetration Barriers

Prescriber preferences, entrenched treatment protocols, and limited awareness in emerging markets may slow CINOBAC's uptake, particularly in regions where older, cheaper antibiotics remain entrenched.

Competitive Landscape

The antimicrobial market features key players such as Pfizer, GlaxoSmithKline, and Merck, who dominate with established products. CINOBAC's success hinges on its unique efficacy profile, safety, and regulatory advantages. Additionally, the influx of biosimilars and generics exerts pressure on pricing and market share.

Financial Trajectory and Revenue Forecast

1. Revenue Potential in Established Markets

In mature markets like North America and Europe, CINOBAC could garner initial revenues of approximately $300 million annually post-launch, assuming a conservative 15% penetration rate within the targeted antibiotic segment. Market growth potential could reach 10% annually, driven by resistance-driven demand.

2. Growth in Emerging Economies

Emerging markets exhibit exponential growth owing to unmet medical needs, with projected revenues reaching $500 million within 5 years of market entry, fueled by expanding healthcare infrastructure and regulatory reforms. An annual growth rate of 20% is plausible as distribution networks expand.

3. Pricing Dynamics

Given the critical nature of CINOBAC and regulatory incentives, premium pricing strategies are conceivable, especially in hospital settings. However, competitive pressures and reimbursement policies could compress margins over time.

4. Cumulative Revenue and Profitability Outlook

By 2030, cumulative revenues across global markets could reach approximately $5 billion, assuming steady growth and market expansion. Profit margins in the initial years may hover around 20%, increasing with scale and market maturity.

Investment and Commercial Strategy Outlook

  • Strategic Licensing and Partnerships: Collaborations with regional manufacturers can accelerate distribution channels, especially in emerging markets.
  • Regulatory Approvals and Fast-Tracking: Securing expedited approvals can bolster early revenue streams.
  • Intellectual Property Management: Protecting patents and developing formulation patents can sustain pricing power against generic competition.

Conclusion

CINOBAC's future hinges on its ability to address urgent clinical needs amid an unfavorable market environment characterized by high R&D costs and stiff competition. Its antimicrobial profile positions it favorably amidst burgeoning resistance trends, which are likely to catalyze sustained demand. Financially, the compound holds promising prospects for robust growth, particularly if strategic partnerships, favorable regulatory environments, and market penetration strategies are optimized.


Key Takeaways

  • Market demand for CINOBAC will be driven primarily by antimicrobial resistance trends and aging populations, making it a valuable asset in the global antimicrobial market.
  • Increased healthcare spending and policy incentives support positive revenue growth in both developed and emerging markets.
  • High R&D costs and patent challenges necessitate strategic patent management, licensing, and differentiation to sustain profitability.
  • Early regulatory approvals and partnerships are crucial to accelerate market entry and adoption, especially in resource-limited settings.
  • Cumulative revenues could reach around $5 billion by 2030, with profitability improving as market share expands and competition is managed.

FAQs

1. What makes CINOBAC a unique candidate in the antimicrobial market?
CINOBAC demonstrates broad-spectrum activity against resistant bacterial strains with a novel mechanism facilitating its efficacy where existing antibiotics fail, positioning it as a critical alternative amid rising antimicrobial resistance.

2. How does antimicrobial resistance impact CINOBAC’s market potential?
AMR acts as a significant driver, creating urgent demand for effective antibiotics. CINOBAC’s activity against resistant bacteria makes it highly sought after, potentially generating sustained demand.

3. What are key risks associated with CINOBAC’s financial trajectory?
Risks include high R&D costs, regulatory hurdles, patent expirations, and aggressive generic competition, all of which could compress margins and delay return on investment.

4. How can pharmaceutical companies maximize CINOBAC’s market potential?
Leveraging strategic partnerships, accelerating regulatory approvals via fast-track programs, focusing on high-growth markets, and securing patent protections are vital strategies.

5. What is the expected timeline for CINOBAC’s revenue growth?
Initial revenue streams are expected within 1-2 years post-launch, with substantial growth anticipated over 5 years, reaching a cumulative revenue around $5 billion by 2030.


Sources
[1] World Health Organization. "Antimicrobial Resistance." 2022.
[2] World Bank. "Global Health Expenditure Database." 2022.
[3] United Nations. "World Population Ageing." 2022.

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