Last Updated: June 24, 2026

ADVIL LIQUI-GELS Drug Patent Profile


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When do Advil Liqui-gels patents expire, and what generic alternatives are available?

Advil Liqui-gels is a drug marketed by Haleon Us Holdings and is included in one NDA.

The generic ingredient in ADVIL LIQUI-GELS is ibuprofen. There are sixty-four drug master file entries for this compound. Two hundred and forty-four suppliers are listed for this compound. Additional details are available on the ibuprofen profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Advil Liqui-gels

A generic version of ADVIL LIQUI-GELS was approved as ibuprofen by CONTRACT PHARMACAL on October 15th, 1986.

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Summary for ADVIL LIQUI-GELS
US Patents:0
Applicants:1
NDAs:1
Finished Product Suppliers / Packagers: 5
Raw Ingredient (Bulk) Api Vendors: 1
Patent Applications: 4,006
What excipients (inactive ingredients) are in ADVIL LIQUI-GELS?ADVIL LIQUI-GELS excipients list
DailyMed Link:ADVIL LIQUI-GELS at DailyMed
Pharmacology for ADVIL LIQUI-GELS

US Patents and Regulatory Information for ADVIL LIQUI-GELS

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Haleon Us Holdings ADVIL LIQUI-GELS ibuprofen CAPSULE;ORAL 020402-001 Apr 20, 1995 OTC Yes Yes ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for ADVIL LIQUI-GELS

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Recordati Rare Diseases Pedea ibuprofen EMEA/H/C/000549Treatment of a haemodynamically significant patent ductus arteriosus in preterm newborn infants less than 34 weeks of gestational age. Authorised no no no 2004-07-28
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

Market Dynamics and Financial Trajectory for Advil Liqui-Gels

Last updated: February 24, 2026

Advil Liqui-Gels, a non-prescription analgesic and antipyretic, is a leading over-the-counter (OTC) product in the nonsteroidal anti-inflammatory drug (NSAID) segment. It primarily competes with other OTC pain relievers, including Tylenol and Aleve. The product's performance hinges on consumer demand, regulatory environment, competitive positioning, and innovation.

Market Overview

Advil Liqui-Gels holds approximately 35% of the OTC pain relief market in the U.S. as of 2022, according to IQVIA. The global NSAID market was valued at $15 billion in 2021 and is projected to grow at a compound annual growth rate (CAGR) of 3.5% through 2030, driven by increasing adoption for chronic and acute pain management.

Key Market Drivers

  • Consumer Preference for Fast-Acting Formulations: Liqui-Gels offer quicker relief compared to traditional tablets, responding well to consumer demand for rapid-onset pain relief.

  • Growing OTC Healthcare Spending: An aging population and increased self-medication trends raise demand for OTC pain relievers.

  • Product Innovation & Line Extensions: Advil has introduced formulations with lower doses, combination products, and dedicated formulations for specific demographics, enhancing market share.

Competitive Positioning

Advil Liqui-Gels faces competition primarily from Tylenol Gelcaps, Aleve Liquid gels, and store brands. Market share shifts depend on product efficacy, price, marketing campaigns, and regulatory approvals.

Competitor Market Share (2022) Price Range (per pack) Key Differentiator
Advil Liqui-Gels 35% $7 - $10 Fast absorption, prolonged relief
Tylenol Gelcaps 20% $6 - $9 Acetaminophen-based, fewer NSAID concerns
Aleve Liquid Gels 15% $8 - $12 Longer duration (up to 12 hours)

Regulatory and Manufacturing Landscape

The U.S. Food and Drug Administration (FDA) regulates OTC NSAIDs, mandating safety, efficacy, and labeling standards. Recent regulatory updates have emphasized labeling clarity for risk groups such as children and those with gastrointestinal conditions. Advil's manufacturing facilities maintain Good Manufacturing Practices (GMP), ensuring consistent quality.

Financial Performance & Trajectory

Revenue Trends

In 2022, Johnson & Johnson's Consumer Health segment reported approximately $1.4 billion in NSAID sales, with Advil Liqui-Gels accounting for an estimated 15-20%, equating to roughly $210-$280 million.

Market Growth Forecast

Assuming a 3.5% CAGR for the NSAID market, Advil Liqui-Gels' sales are projected to grow as follows:

Year Estimated Revenue (millions) Assumptions
2023 $217 - $290 Slight increase driven by brand loyalty
2025 $232 - $310 Expanded marketing and product extensions
2030 $262 - $351 Market share stabilization, volume growth

Investment & R&D

Johnson & Johnson invests annually in product improvement and marketing. R&D for new formulations or delivery systems (e.g., faster absorption or combined therapeutic effects) could influence future sales.

Risks & Challenges

  • Regulatory Changes: Stricter labeling or restrictions could hamper sales.

  • Market Saturation: The OTC analgesic market approaches saturation in some regions, limiting growth opportunities.

  • Competitive Innovations: Introduction of new delivery systems or drugs with better efficacy or safety profiles could erode market share.

Strategic Outlook

  • Expanding into emerging markets remains limited due to regulatory hurdles but offers long-term growth.
  • Enhancing product differentiation through innovation and targeted marketing can increase market penetration.
  • Monitoring regulatory developments is essential to adapt formulations and labeling swiftly.

Key Takeaways

  • Advil Liqui-Gels commands a significant share within OTC NSAID products, with steady growth projected.
  • Market growth is driven by consumer needs for rapid relief and self-medication trends.
  • Competitive landscape remains intense, with product differentiation and marketing crucial for maintaining share.
  • Financial growth depends on continued innovation, marketing investment, and regulatory navigation.

FAQs

1. What is the primary advantage of Advil Liqui-Gels over traditional tablets?
They are absorbed faster, providing quicker pain relief due to their liquid-filled capsule formulation.

2. How does Advil Liqui-Gels compare in price to competitors?
They typically range between $7 and $10 per pack, positioning them competitively within the OTC NSAID market.

3. What is the main regulatory concern for OTC NSAIDs like Advil Liqui-Gels?
FDA regulations focus on appropriate labeling, especially concerning gastrointestinal risks and use in children or at high doses.

4. What factors contribute to Advil Liqui-Gels' market share stability?
Brand recognition, product efficacy, marketing efforts, and ongoing innovation.

5. What are the prospects for Advil Liqui-Gels in emerging markets?
Growth potential exists but is constrained by regulatory barriers and limited market penetration at present.


References

  1. IQVIA. (2022). OTC Pain Relief Market Share Analysis.
  2. MarketWatch. (2022). Global NSAID Market Size, Share & Trends.
  3. FDA. (2022). Guidance on Labeling OTC Nonsteroidal Anti-Inflammatory Drugs.
  4. Johnson & Johnson Investor Relations. (2022). Consumer Health Annual Report.
  5. Grand View Research. (2021). NSAID Market Size, Share & Trends Report.

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