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Last Updated: December 12, 2025

ADVIL LIQUI-GELS Drug Patent Profile


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When do Advil Liqui-gels patents expire, and what generic alternatives are available?

Advil Liqui-gels is a drug marketed by Haleon Us Holdings and is included in one NDA.

The generic ingredient in ADVIL LIQUI-GELS is ibuprofen. There are sixty-four drug master file entries for this compound. Two hundred and forty-six suppliers are listed for this compound. Additional details are available on the ibuprofen profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Advil Liqui-gels

A generic version of ADVIL LIQUI-GELS was approved as ibuprofen by STRIDES PHARMA INTL on September 24th, 1986.

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Summary for ADVIL LIQUI-GELS
US Patents:0
Applicants:1
NDAs:1
Finished Product Suppliers / Packagers: 5
Raw Ingredient (Bulk) Api Vendors: 1
Patent Applications: 3,881
What excipients (inactive ingredients) are in ADVIL LIQUI-GELS?ADVIL LIQUI-GELS excipients list
DailyMed Link:ADVIL LIQUI-GELS at DailyMed
Drug patent expirations by year for ADVIL LIQUI-GELS
Pharmacology for ADVIL LIQUI-GELS

US Patents and Regulatory Information for ADVIL LIQUI-GELS

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Haleon Us Holdings ADVIL LIQUI-GELS ibuprofen CAPSULE;ORAL 020402-001 Apr 20, 1995 OTC Yes Yes ⤷  Get Started Free ⤷  Get Started Free ⤷  Get Started Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for ADVIL LIQUI-GELS

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Recordati Rare Diseases Pedea ibuprofen EMEA/H/C/000549Treatment of a haemodynamically significant patent ductus arteriosus in preterm newborn infants less than 34 weeks of gestational age. Authorised no no no 2004-07-28
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

Market Dynamics and Financial Trajectory for Advil Liqui-Gels

Last updated: July 30, 2025

Introduction

Advil Liqui-Gels, a leading over-the-counter (OTC) analgesic and anti-inflammatory drug, occupies a significant position within the global pharmaceutical market, primarily driven by its active ingredient, ibuprofen. As a fast-acting capsule, Advil Liqui-Gels appeals to consumers seeking rapid pain relief, contributing to its sustained consumer preference. Analyzing its market dynamics and financial trajectory involves examining various factors, including market demand, competitive landscape, regulatory factors, consumer behaviors, and broader industry trends influencing OTC analgesics.

Market Dynamics

Consumer Demand and Market Segmentation

The global OTC analgesics market is robust, driven by increasing incidences of chronic and acute pain, aging populations, and rising consumer awareness of self-medication options. Advil Liqui-Gels benefits significantly from consumer preference for fast-acting formulations, which have gained popularity over traditional tablets and caplets [1].

Segment-wise, the demand for OTC analgesics like Advil Liqui-Gels spans multiple demographics, including:

  • Elderly consumers: Increased prevalence of chronic pain and arthritis.
  • Active adults: Sports injuries and musculoskeletal discomfort.
  • Parents: Children's minor pain management, with formulations catered to pediatric needs.

Market Drivers

Several factors propel Advil Liqui-Gels’ market growth:

  • Product Efficacy and Convenience: The liqui-gel form provides quicker absorption of ibuprofen, leading to faster pain relief, a key differentiator [2].
  • Brand Recognition: As part of Johnson & Johnson's consumer health portfolio, Advil benefits from strong brand equity and consumer trust.
  • Regulatory Environment: Favorable regulatory frameworks in key markets facilitate OTC sales, although stringent controls in some regions to prevent misuse persist.
  • Expanding Emerging Markets: Growing middle-class populations in Asia-Pacific and Latin America increase OTC analgesic consumption.

Competitive Landscape

Advil Liqui-Gels face competition from several brands, including Motrin IB, Aleve, and store brands offering similar ibuprofen formulations. The competitive advantage hinges on:

  • Product Differentiation: Fast absorption, packaging, and marketing.
  • Pricing Strategies: Maintaining attractive price points amid generics proliferation.
  • Distribution Channels: Extensive presence in pharmacies, supermarkets, and online marketplaces.

Regulatory and Legal Factors

Regulatory bodies like the FDA in the US and EMA in Europe regulate OTC drug approvals, labeling, and marketing claims. Recent trends include increased scrutiny over sodium content and gastrointestinal safety associated with NSAID use [3]. Compliance costs and legal risks influence market strategies and product formulations.

Financial Trajectory

Historical Performance

Advil Liqui-Gels, as part of Johnson & Johnson’s consumer health segment, has historically contributed significantly to revenue streams. The segment posted steady growth from 2015 to 2020, with OTC analgesics accounting for approximately 25-30% of total consumer health revenue [4]. The product’s contribution remained resilient amid economic fluctuations due to the consistent demand for pain relief.

Revenue Growth and Projections

Forecasts indicate moderate to strong growth in OTC analgesics, including Advil Liqui-Gels, driven by factors such as:

  • Increased Health Awareness: Consumers increasingly prefer OTC solutions over prescriptions for minor ailments.
  • Digital Marketing and E-commerce: Growth in online pharmacy sales enhances accessibility and market reach.
  • Population Aging: The global rise in older age groups sustains demand for anti-inflammatory medications.

Analysts project a compounded annual growth rate (CAGR) of approximately 3-5% for the global OTC pain relievers segment over the next five years [5].

Profitability and Margin Outlook

Advil Liqui-Gels benefits from high brand recognition, allowing premium pricing strategies. The gross margins are robust, estimated at around 60-65%, driven by economies of scale and cost efficiencies in manufacturing. However, increased marketing, R&D, and regulatory compliance expenses could exert pressure on profit margins.

Risks and Challenges

  • Generic Competition: The expiry of patents or exclusivity periods could lead to increased generic copying, compressing profit margins.
  • Regulatory Hurdles: Stringent safety regulations, especially concerning NSAID-related gastrointestinal and cardiovascular risks, may necessitate reformulations and advertising restrictions.
  • Market Saturation: Mature markets face limited growth potential, necessitating geographic expansion or product diversification.

Strategic Outlook

Johnson & Johnson's strategy involves emphasizing innovation—such as developing formulations with reduced gastrointestinal risks—and expanding into emerging markets. Digital and e-commerce expansion remains central, leveraging data analytics to identify consumer preferences. Partnerships for distribution and local regulatory navigation are pivotal for penetrating new geographies.

Conclusion

Advil Liqui-Gels continues to enjoy a strong market position, supported by consumer preference for fast-acting OTC analgesics, brand strength, and expanding global reach. Its financial trajectory reflects steady growth, poised to benefit from demographic shifts and evolving consumer behaviors. However, competitive pressures, regulatory environments, and patent expiration risks necessitate proactive innovation and strategic adaptation.


Key Takeaways

  • Advil Liqui-Gels sustains growth through its unique fast-acting formulation and strong brand presence.
  • The global OTC analgesics market is expected to grow at 3-5% CAGR, driven by aging populations and consumer health awareness.
  • Competition from generics and regulatory challenges represent significant risks; innovation and geographic expansion remain crucial.
  • High margins are sustainable but require cost management amidst regulatory and marketing expenses.
  • Digital commerce and emerging markets are key avenues for future growth.

FAQs

1. How does Advil Liqui-Gels differentiate itself from generic ibuprofen products?
Advil Liqui-Gels offer faster absorption and relief compared to traditional tablets due to their liqui-gel formulation, coupled with strong brand recognition and trusted efficacy, setting them apart from unbranded generics.

2. What are the primary risks facing Advil Liqui-Gels' market growth?
Risks include increased competition from generics, regulatory restrictions related to NSAID safety, patent expirations, and shifts in consumer preferences towards alternative pain management options.

3. How has digital sales influenced Advil Liqui-Gels' market presence?
E-commerce platforms and online pharmacies have expanded accessibility, especially amid the COVID-19 pandemic, enabling wider distribution and targeted marketing, thereby supporting sales growth.

4. What strategies can Johnson & Johnson employ to sustain Advil Liqui-Gels’ market share?
Innovating with safer formulations, expanding into emerging markets, bolstering digital marketing, and forming strategic partnerships can help sustain and grow its market share.

5. What is the outlook for Advil Liqui-Gels’ profitability in the next five years?
If current trends persist, Advil Liqui-Gels can expect stable to modest growth in profitability, leveraging brand loyalty, margin management, and expanded market penetration, provided regulatory and competitive challenges are effectively navigated.


References

[1] Statista (2022). OTC Painkillers Market Share and Consumer Preferences.
[2] Johnson & Johnson Annual Report (2021). Consumer Healthcare Segment Overview.
[3] FDA (2022). NSAID Safety Communications and Regulatory Updates.
[4] Johnson & Johnson (2021). Quarterly Financial Reports.
[5] Global Market Insights (2022). OTC Analgesics Market Forecasts.

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