Last updated: April 25, 2026
Who Supplies Metoclopramide Hydrochloride to Pharma and Generics?
Metoclopramide hydrochloride (CAS 6138-23-4) is sold globally as an API (active pharmaceutical ingredient) and as finished-dose intermediates by established chemical and generic-API manufacturers. Below is a supplier map focused on companies that consistently appear in commercial supply chains for metoclopramide hydrochloride API and related upstream manufacturing.
Which Companies Supply Metoclopramide Hydrochloride API?
Commercial API suppliers (global)
The following suppliers are active in supplying small-molecule generic APIs, including metoclopramide hydrochloride, for distributor, toll-manufacturing, and finished-dosage supply chains:
| Supplier |
Supply role in ecosystem |
What they typically provide |
Notes for buyers |
| Hangzhou Keyingchem |
API manufacturing |
Metoclopramide hydrochloride (API-grade) |
Commonly listed by chemical-distribution channels for generic API demand |
| Cangzhou Grandsky |
API manufacturing |
Metoclopramide hydrochloride |
Often appears as an API source for export markets |
| Zhejiang Hisun Pharma (Hisun) |
API and pharma chemicals |
Metoclopramide-related small-molecule production |
Large-scale small-molecule manufacturing capacity used by downstream manufacturers |
| Shaanxi Huike (Huike) |
API manufacturing |
Metoclopramide hydrochloride (API) |
Commonly listed for generic API programs |
| Hubei Kelong |
API manufacturing |
Metoclopramide hydrochloride |
Participates in bulk chemical/API exports |
| MedChemExpress (MCE) |
Research-grade supplier (lab chemicals) and distributors |
Metoclopramide hydrochloride (non-GMP variants exist) |
Useful for R&D sourcing, not always for finished-dose GMP supply |
Metoclopramide is an older, widely used generic product. Many suppliers exist across China and other manufacturing hubs; the supplier set above reflects repeat visibility in commercial sourcing channels rather than a comprehensive register of every verified API site.
What Supplier Types Exist for Metoclopramide Hydrochloride?
Primary supply categories
Metoclopramide hydrochloride procurement typically comes through three channels:
-
API manufacturers (GMP)
Provide metoclopramide hydrochloride as an API for finished-dose contract manufacturers.
-
API trading/distribution houses
Source API in bulk from GMP plants and supply distributors or finished-dose manufacturers with paperwork bundles (COA/CoC and specs).
-
R&D/lab-grade chemical suppliers
Provide metoclopramide hydrochloride for analytical work. These may be “for research use only” and may not support commercial GMP release.
How to Read Supplier Relevance for Metoclopramide Hydrochloride
Key decision filters used in procurement
For metoclopramide hydrochloride, buyers typically screen suppliers using these procurement-grade criteria:
- Manufacturing compliance: GMP for APIs (e.g., compliance indicated via regulatory inspections or verified quality documentation practices).
- Spec alignment: alignment to the buyer’s pharmacopeia target (USP/EP/BP) or internal method specs.
- Document pack: COA/CoC, impurity profile, residual solvents, polymorph info if applicable, and stability program evidence if required.
- Form factor: salt form confirmation (hydrochloride), packaging (drums/bags), and shelf-life.
- Supply continuity: ability to sustain forecasted volumes and lead times.
What Finished-Dose Supply Chain Uses Metoclopramide Hydrochloride?
Downstream users
Metoclopramide hydrochloride API is used in finished-dose products such as:
- Oral tablets
- Oral solutions
- Injectables (where formulations specify the hydrochloride salt)
- Pediatric dosing formulations (where regional labeling supports use)
Because it is widely generic, demand is often distributed across:
- finished-dose contract manufacturers,
- regional generic drug producers,
- hospital procurement for certain formulations.
Supplier Selection Snapshot for Business Use
Recommended supplier shortlisting approach
A practical shortlist usually includes:
- Two GMP API manufacturers (for bid comparison and supply redundancy)
- One secondary backup source (for continuity under shortages)
- One distributor/trader (if spot volume or fast lead times matter)
Key Takeaways
- Metoclopramide hydrochloride is a widely sourced generic API with supply concentrated among established small-molecule API manufacturers and distributors.
- Supplier selection should prioritize GMP API capability, pharmacopeia spec alignment, and full documentation support (COA/CoC and impurity profile).
- The most commercially relevant suppliers are those with repeat visibility across generic API sourcing channels, including large China-based API manufacturers and established distributors.
FAQs
1) Is metoclopramide hydrochloride widely available as an API?
Yes. It is a legacy generic active, so the commercial supply base is broad and includes multiple manufacturers and distributors.
2) Are all metoclopramide hydrochloride suppliers suitable for commercial GMP use?
No. Some suppliers focus on R&D/lab-grade chemicals. Commercial use requires GMP-capable API supply and a documentation pack aligned to finished-dose quality requirements.
3) What’s the most important procurement criterion for metoclopramide hydrochloride?
Spec compliance (pharmacopeia or internal) and the ability to supply consistent impurity profiles with full batch documentation.
4) Can distributors source metoclopramide hydrochloride from multiple GMP plants?
Yes. Many distributors consolidate from several API plants to manage pricing, lead time, and continuity.
5) What downstream dosage forms drive API demand most?
Oral tablets and solutions typically drive broad baseline demand; injectable formulations add specific batch demand where market regulations and tender cycles apply.
References
[1] PubChem. Metoclopramide Hydrochloride (CAS 6138-23-4).
[2] ECHA. Substance information for metoclopramide (and related salts).
[3] USP–NF. Metoclopramide Hydrochloride monograph (specification framework).
[4] European Pharmacopoeia (Ph. Eur.). Metoclopramide hydrochloride monographs (specification framework).
[5] Vendor catalog listings for metoclopramide hydrochloride API from global chemical distributors and API manufacturers (industry supply-chain visibility).
