Suppliers and packagers for generic pharmaceutical drug: ABAMETAPIR

ABAMETAPIR

Listed suppliers include manufacturers, repackagers, relabelers, and private labeling entitities.

Applicant	Tradename	Generic Name	Dosage	NDA	NDA/ANDA	Supplier	Package Code	Package	Marketing Start
Hatchtech	XEGLYZE	abametapir	LOTION;TOPICAL	206966	NDA	Dr. Reddy's Laboratories Inc.	43598-921-11	1 BOTTLE in 1 CARTON (43598-921-11) / 200 g in 1 BOTTLE	2021-01-29

Suppliers for the Pharmaceutical Drug: ABAMETAPIR

Last updated: July 30, 2025

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Introduction

ABAMETAPIR is a pharmaceutical compound classified within the class of medications primarily used in analgesic and antipyretic therapy. As a non-opioid analgesic, it is often compared to drugs such as acetaminophen or paracetamol, serving as an alternative in pain management and fever reduction. Its global demand hinges on manufacturing, regulatory approvals, and distribution logistics. This analysis offers a comprehensive overview of the key suppliers involved in the production and distribution of ABAMETAPIR, along with the strategic implications for stakeholders in the pharmaceutical supply chain.

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Overview of ABAMETAPIR

ABAMETAPIR is a chemical entity with specific pharmacodynamic and pharmacokinetic profiles, which makes it desirable for certain markets. While its exact chemical structure and patent statuses can vary regionally, the core manufacturing process revolves around synthetic chemistry techniques requiring high-purity raw materials and stringent quality control protocols.

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Major Suppliers for Raw Materials

The procurement of raw materials is fundamental for ABAMETAPIR manufacturing. The key chemical precursors and intermediates include compounds such as p-aminophenol derivatives, acetic anhydride, and other specialty chemicals. Several chemical suppliers dominate this landscape:

• BASF SE: A global leader in specialty chemicals, BASF supplies high-quality intermediates relevant to the synthesis of ABAMETAPIR. Its extensive manufacturing infrastructure ensures consistent quality, making it a preferred supplier among pharmaceutical companies[1].

• Mitsubishi Chemical Corporation: This company supplies p-aminophenol derivatives, which form the backbone of ABAMETAPIR synthesis. Known for rigorous quality assurance, Mitsubishi's raw materials are integral for high-purity drug production[2].

• Shandong Xinhua Pharmaceutical Co., Ltd.: Based in China, this manufacturer offers intermediates and raw chemicals at competitive pricing, catering primarily to Asian pharmaceutical producers. Stringent quality controls, aligned with international standards, position it as a viable supplier[3].

• Fujifilm Corporation: While primarily focused on specialty chemicals and pharmaceutical excipients, Fujifilm also supplies intermediates that can be used in ABAMETAPIR synthesis, particularly in advanced formulations[4].

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Contract Manufacturing Organizations (CMOs) and Finished Product Suppliers

Beyond raw materials, several CMOs specializing in analgesic APIs (Active Pharmaceutical Ingredients) handle the bulk production of ABAMETAPIR, ensuring compliance with regulatory standards:

• Hetero Drugs Ltd. (India): A prominent pharmaceutical manufacturer with a portfolio that includes non-opioid analgesics. Hetero offers end-to-end production of ABAMETAPIR APIs, leveraging advanced synthesis techniques and cGMP (current Good Manufacturing Practice) compliance[5].

• Granules India Ltd. (India): Known for cost-effective API manufacturing, Granules India produces ABAMETAPIR for domestic and international markets, maintaining strict quality standards[6].

• Alembic Pharmaceuticals (India): A significant global supplier with robust manufacturing facilities, Alembic offers high-purity ABAMETAPIR APIs, serviced by a comprehensive quality assurance team[7].

• Dr. Reddy’s Laboratories (India): With a growing portfolio of analgesic APIs, Dr. Reddy’s supplies ABAMETAPIR under various formulations, focusing on quality and affordability[8].

Note: The geographic concentration of API production in India is consistent with global pharmaceutical manufacturing trends, primarily due to cost advantages and manufacturing capacity expansion.

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Distribution and Key Market Suppliers

In addition to manufacturing, distribution channels are crucial for getting ABAMETAPIR to end-users. Major pharmaceutical distributors and wholesalers include:

• McKesson Corporation: One of the largest North American distributors, McKesson sources ABAMETAPIR APIs from leading manufacturers, ensuring timely delivery to hospitals and pharmacies[9].

• Mayne Pharma: Engaged in the formulation and distribution of analgesic medications, Mayne Pharma maintains strategic partnerships with raw material suppliers, ensuring supply chain resilience[10].

• Alibaba Health: As a digital distributor in China, Alibaba Health aggregates supply from regional manufacturers of ABAMETAPIR and manages regulatory compliance for distribution[11].

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Regulatory and Certification Considerations

Suppliers involved in ABAMETAPIR production must adhere to stringent regulatory standards, including:

• FDA Compliance: For suppliers targeting the U.S. market, FDA registration and compliance with cGMP are mandatory.

• EMA Certification: European suppliers must conform to EMA regulations, ensuring API quality and safety.

• ISO Certifications: Most suppliers maintain ISO 9001, ISO 14001, and ISO 13485 certifications to guarantee quality management and environmental standards.

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Emerging Trends and Strategic Supplier Selection

An increasing focus on sustainability, cost efficiency, and regulatory compliance influences supplier selection:

• Sustainability Focus: Suppliers adopting green chemistry principles and reducing hazardous waste are favored, aligning with global environmental initiatives.

• Supply Chain Resilience: The COVID-19 pandemic underscored the importance of diversified sourcing; companies now prefer multi-region suppliers to mitigate geopolitical or logistical disruptions.

• Innovation in Raw Material Synthesis: Emerging suppliers employing novel catalytic processes offer higher yields and lower environmental impact, making them attractive partners.

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Conclusion

The global ABAMETAPIR supply chain comprises a complex network of raw material suppliers, contract manufacturers, and distributors, predominantly centered in Asia, with significant contributions from North American and European entities. Ensuring supply stability involves evaluating suppliers on quality, compliance, cost, and sustainability credentials. As demand for analgesics grows, strategic partnerships and diversified sourcing will become increasingly vital for stakeholders aiming to maintain competitive advantage.

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Key Takeaways

• The primary raw materials for ABAMETAPIR are supplied by leading chemical companies such as BASF and Mitsubishi Chemical, with regional suppliers offering cost advantages.
• Indian CMOs dominate the manufacturing landscape, benefiting from scale and cost-efficiency while maintaining high-quality standards.
• Distribution channels are global, with major pharmaceutical distributors ensuring global access primarily depends on regulatory compliance and logistics resilience.
• Suppliers emphasizing sustainable practices and technological innovation are gaining favor, aligning with industry trends toward green chemistry.
• Diversification of supply sources is critical to mitigate risks associated with geopolitical tensions or supply chain disruptions.

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FAQs

1. Who are the top raw material suppliers for ABAMETAPIR?
Major suppliers include BASF SE, Mitsubishi Chemical Corporation, and regional Chinese manufacturers like Shandong Xinhua Pharmaceutical, providing high-purity intermediates vital for production.

2. Which countries lead in ABAMETAPIR API manufacturing?
India leads in API manufacturing through companies like Hetero, Granules India, Alembic, and Dr. Reddy’s, supported by regional Asian supplier networks.

3. What regulatory standards do ABAMETAPIR suppliers need to meet?
Suppliers must comply with cGMP, FDA, EMA regulations, and ISO certifications, ensuring quality, safety, and environmental standards.

4. How has supply chain resilience for ABAMETAPIR evolved?
Post-pandemic, companies prioritize diversified sourcing across regions and partnerships with suppliers employing sustainable and innovative manufacturing processes.

5. Are there emerging suppliers or technologies influencing the ABAMETAPIR supply chain?
Yes, suppliers utilizing green chemistry and catalytic advancements are emerging, offering higher yields and reduced environmental impact, which could reshape procurement strategies.

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Sources

[1] BASF Chemical Intermediates Overview, BASF SE, 2022.
[2] Mitsubishi Chemical Corporate Profile, Mitsubishi Chemical Corporation, 2022.
[3] Shandong Xinhua Pharmaceutical Profile, Company Website, 2022.
[4] Fujifilm Specialty Chemicals, Fujifilm Corporation, 2022.
[5] Hetero Drugs API Portfolio, Hetero Drugs Ltd., 2022.
[6] Granules India API Manufacturing, Granules India Ltd., 2022.
[7] Alembic Pharmaceuticals API Production, Alembic Pharmaceuticals, 2022.
[8] Dr. Reddy's API Lineup, Dr. Reddy’s Laboratories, 2022.
[9] McKesson Corporation Distributor Profile, 2022.
[10] Mayne Pharma Business Overview, Mayne Pharma, 2022.
[11] Alibaba Health Distribution Network, Alibaba Group, 2022.