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Serving 500+ biopharmaceutical companies globally:

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Generated: September 25, 2017

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Title: Methods of imaging using osmotically stabilized microbubble preparations
Abstract:A microbubble preparation formed of a plurality of microbubbles comprising a first gas and a second gas surrounded by a membrane such as a surfactant, wherein the first gas and the second gas are present in a molar ratio of from about 1:100 to about 1000:1, and wherein the first gas has a vapor pressure of at least about (760-x) mm Hg at 37.degree. C., where x is the vapor pressure of the second gas at 37.degree. C., and wherein the vapor pressure of each of the first and second gases is greater than about 75 mm Hg at 37.degree. C.; also disclosed are methods for preparing microbubble compositions, including compositions that rapidly shrink from a first average diameter to a second average diameter less than about 75% of the first average diameter and are stabilized at the second average diameter; methods and kits for preparing microbubbles; and methods for using such microbubbles as contrast agents.
Inventor(s): Schutt; Ernest G. (San Diego, CA), Anderson; Charles David (Lebanon, NJ), Evitts; David P. (La Jolla, CA)
Assignee: Alliance Pharmaceuticals Corp. (San Diego, CA)
Application Number:08/841,846
Patent Claim Types:
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Use; Dosage form; Compound;

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International Patent Family for Patent: ► Subscribe

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Denmark0711179► Subscribe
Germany69434119► Subscribe
China1182373► Subscribe
Finland973496► Subscribe
Hong Kong1013403► Subscribe
Japan4229918► Subscribe
JapanH11501305► Subscribe
South Korea100407755► Subscribe
Mexico9706402► Subscribe
Norway973489► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving 500+ biopharmaceutical companies globally:

Chubb
Teva
Medtronic
Merck
Citi
Deloitte
Moodys
Mallinckrodt
US Department of Justice
Healthtrust

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