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Last Updated: March 28, 2024

Details for Patent: 5,543,150


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Summary for Patent: 5,543,150
Title: Method of progesterone delivery and affect thereof
Abstract:The present invention teaches that relatively low levels of serum progesterone, 1 to 6 ng/ml, may be used to prevent endometrial cancer. The vaginal delivery of progesterone using a cross-linked polycarboxylic polymer produces this low serum progesterone level while also providing the full secretory transformation of the endometrium, indicating the efficacy of the progesterone. Such low levels of serum progesterone will decrease the risk of breast cancer experienced by women undergoing hormone replacement therapy ("HRT") and minimize the potential of other undesirable progesterone associated side effects.
Inventor(s): Bologna; William J. (New York, NY), Levine; Howard L. (Oceanside, NY)
Assignee: Columbia Laboratories, Inc. (Coconut Grove, FL)
Application Number:08/122,371
Patent Claim Types:
see list of patent claims
Use; Delivery; Device;

Drugs Protected by US Patent 5,543,150

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
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