|Title:||Method of treating tumors in mammals with 2',2'-difluoronucleosides|
|Abstract:||A method of treating susceptible neoplasms in mammals comprising administering to a mammal in need of such treatment a pharmaceutically effective amount of a compound of the formula ##STR1## wherein: R.sup.1 is hydrogen; R.sup.2 is a base defined by one of the formulae ##STR2## X is C-R.sup.4 ; R.sup.3 is hydrogen; R.sup.4 is hydrogen, C.sub.1 -C.sub.4 alkyl, bromo, fluoro, chloro or iodo; and the pharmaceutically-acceptable salts thereof.|
|Inventor(s):||Grindey; Gerald B. (Indianapolis, IN), Hertel; Larry W. (Indianapolis, IN)|
|Assignee:||Eli Lilly and Company (Indianapolis, IN)|
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