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Details for Patent: RE44733

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Patent RE44733 protects BRIDION and is included in one NDA.

This patent has thirty-nine patent family members in twenty-nine countries.

Summary for Patent: RE44733

Title:6-mercapto-cyclodextrin derivatives:reversal agents for drug-induced neuromuscular block
Abstract: Disclosed is a 6-mercapto-cyclodextrin derivative having general formula (I) wherein m is 0-7 and n is 1-8 and m+n=7 or 8; R is (C.sub.1-6)alkylene, optionally substituated with 1-3 OH groups, or (CH.sub.2).sub.o-phenylene-(CH.sub.2).sub.p--; o and p are independently 0-4; X is COOH, CONHR.sub.1, NHCOR.sub.2, SO.sub.2OH, PO(OH).sub.2, O(CH.sub.2--CH.sub.2--O).sub.q--H, OH or tetrazol-5-yl; R.sub.1 is H or (C.sub.1-3)alkyl; R.sub.2 is carboxyphenyl; q is 1-3; or pharmaceutically acceptable salts thereof. The 6-mercaptocyclodextrin derivative is highly suitable for use in the reversal of drug-induced neuromuscular block. ##STR00001##
Inventor(s): Zhang; Mingiang (Montreal, CA), Palin; Ronald (Banton, GB), Bennett; Jonathan (Edinburgh, GB)
Assignee: Merck Sharp & Dohme B.V. (Haarlem, NL)
Application Number:13/432,742
Patent Claim Types:
see list of patent claims
Compound; Composition; Device; Use;

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Organon Sub Merck
BRIDION
sugammadex sodium
SOLUTION;INTRAVENOUS022225-002Dec 15, 2015RXNoRE44733► subscribeYY REVERSAL OF DRUG-INDUCED NEUROMUSCLUAR BLOCK
Organon Sub Merck
BRIDION
sugammadex sodium
SOLUTION;INTRAVENOUS022225-001Dec 15, 2015RXYesRE44733► subscribeYY REVERSAL OF DRUG-INDUCED NEUROMUSCLUAR BLOCK
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Foreign Priority and PCT Information for Patent: RE44733

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
99309558Nov 29, 1999
PCT Information
PCT FiledNovember 23, 2000PCT Application Number:PCT/EP00/11789
PCT Publication Date:June 07, 2001PCT Publication Number: WO01/40316

Non-Orange Book Patents for Patent: RE44733

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,949,527 6-Mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block► subscribe
6,670,340 6-Mercapto-cyclodextrin derivatives:reversal agents for drug-induced neuromuscular block► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Because of the complexity of determining patent expiration dates it is advisable to have patent counsel verify freedom to operate.

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International Patent Family for Patent: RE44733

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina026605► subscribe
Austria288450► subscribe
Australia5438001► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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