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Last Updated: May 4, 2024

Details for Patent: RE44733


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Which drugs does patent RE44733 protect, and when does it expire?

Patent RE44733 protects BRIDION and is included in one NDA.

This patent has forty-two patent family members in thirty countries.

Summary for Patent: RE44733
Title:6-mercapto-cyclodextrin derivatives:reversal agents for drug-induced neuromuscular block
Abstract: Disclosed is a 6-mercapto-cyclodextrin derivative having general formula (I) wherein m is 0-7 and n is 1-8 and m+n=7 or 8; R is (C.sub.1-6)alkylene, optionally substituated with 1-3 OH groups, or (CH.sub.2).sub.o-phenylene-(CH.sub.2).sub.p--; o and p are independently 0-4; X is COOH, CONHR.sub.1, NHCOR.sub.2, SO.sub.2OH, PO(OH).sub.2, O(CH.sub.2--CH.sub.2--O).sub.q--H, OH or tetrazol-5-yl; R.sub.1 is H or (C.sub.1-3)alkyl; R.sub.2 is carboxyphenyl; q is 1-3; or pharmaceutically acceptable salts thereof. The 6-mercaptocyclodextrin derivative is highly suitable for use in the reversal of drug-induced neuromuscular block. ##STR00001##
Inventor(s): Zhang; Mingiang (Montreal, CA), Palin; Ronald (Banton, GB), Bennett; Jonathan (Edinburgh, GB)
Assignee: Merck Sharp & Dohme B.V. (Haarlem, NL)
Application Number:13/432,742
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent RE44733
Patent Claim Types:
see list of patent claims
Compound; Composition; Device; Use;

Drugs Protected by US Patent RE44733

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Msd Sub Merck BRIDION sugammadex sodium SOLUTION;INTRAVENOUS 022225-002 Dec 15, 2015 AP RX Yes No ⤷  Try a Trial ⤷  Try a Trial Y Y REVERSAL OF DRUG-INDUCED NEUROMUSCULAR BLOCK ⤷  Try a Trial
Msd Sub Merck BRIDION sugammadex sodium SOLUTION;INTRAVENOUS 022225-001 Dec 15, 2015 AP RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y REVERSAL OF DRUG-INDUCED NEUROMUSCULAR BLOCK ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: RE44733

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
99309558Nov 29, 1999
PCT Information
PCT FiledNovember 23, 2000PCT Application Number:PCT/EP00/11789
PCT Publication Date:June 07, 2001PCT Publication Number: WO01/40316

International Family Members for US Patent RE44733

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 026605 ⤷  Try a Trial
Austria 288450 ⤷  Try a Trial
Australia 5438001 ⤷  Try a Trial
Australia 776536 ⤷  Try a Trial
Brazil 0015947 ⤷  Try a Trial
Canada 2390463 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.