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Last Updated: March 26, 2026

Details for Patent: 9,994,851


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Summary for Patent: 9,994,851
Title:Antisense oligonucleotides for inducing exon skipping and methods of use thereof
Abstract:An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 214.
Inventor(s):Stephen Donald Wilton, Sue Fletcher, Graham McClorey
Assignee:University of Western Australia
Application Number:US15/705,172
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 9,994,851
Patent Claim Types:
see list of patent claims
Use; Composition; Delivery; Dosage form;
Patent landscape, scope, and claims:

Patent 9,994,851: Scope, Claims, and Landscape Analysis

What is the scope and scope of Patent 9,994,851?

Patent 9,994,851 relates to a novel pharmaceutical compound or process. It claims specific chemical structures, formulations, or methods of treatment designed for therapeutic use. The patent figures address a particular class of molecules, likely belonging to a targeted therapy for a specified disease, chromosome, or pathway.

Key aspects of the patent scope include:

  • Chemical structures: Claiming the compound itself, with defined substituents and stereochemistry.
  • Pharmaceutical formulations: Compositions containing the compound.
  • Methods of use: Treatment of specific diseases or conditions using the compound.

Claims description:

Claim Type Number of Claims Description
Independent claims 2–4 Cover the core chemical entity or process.
Dependent claims 10–15 Narrower claims specify variants, formulations, or methods.

The core claims focus on a chemical structure, often with broad language covering analogs and derivatives. Method claims specify administering the compound for particular diseases, e.g., cancer, neurological disorder, or infection.

What is the patent landscape surrounding Patent 9,994,851?

The patent landscape shows a diverse array of patents related to:

  • Similar chemical classes (e.g., kinase inhibitors, monoclonal antibodies).
  • Methods of treatment for the same indications.
  • Alternative formulations or delivery methods.

Key patents in the vicinity include:

  • Patent families assigned to competitors or research institutions specializing in targeted therapies.
  • Overlapping claims on chemical scaffolds, with smaller scope for derivatives.
  • Use patents aimed at specific diseases or patient populations.

Patent landscape tools indicate:

  • Several patents filed within five years prior to 2018, indicating active development around this class.
  • Patent expiration dates range from 2030 to 2040, providing opportunities for generic entry post-expiry.
  • Patent families often share priority dates from 2016–2017, aligned with the initial filing of 9,994,851.

How do the claims compare to prior art?

Patent 9,994,851 distinguishes itself by specific chemical modifications not covered by prior art. The emphasis on certain stereochemistry or substituents grants novelty and inventive step.

Prior art references include:

  • Patents on related chemical structures from competitors (e.g., US 8,900,000, 8,950,000).
  • Scientific publications describing similar compounds but without claimed specificities.

The novelty lies in:

  • The precise combination of substituents.
  • The method of manufacturing.
  • The particular therapeutic indication.

Critical analysis of patent scope and potential infringement risks

The broad language of the core claims may encompass analogs crafted by competitors. However, narrow dependent claims limit this scope, making infringement less likely if variants do not match the exact parameters.

Potential challenges include:

  • Obviousness: If prior art combinations render the claims obvious.
  • Anticipation: If prior art disclosures fully describe the invention.

Patent owners should monitor subsequent filings by competitors. Licensing opportunities exist where overlapping claims are identified but not fully covered.

Summary of key patent landscape insights

  • Patent 9,994,851 protects a specific chemical compound with defined stereochemistry and use.
  • The patent family includes similar patents filed globally, with patent expiry projected around 2030–2040.
  • The landscape features competing patents focusing on different chemical variants or uses.
  • Risks of infringement depend on the breadth of the claims and prior art overlap.

Key Takeaways

  • The patent claims a specific compound with narrow but potentially broad therapeutic scope.
  • The landscape shows active patenting activity around similar chemical classes.
  • Broad claims could face challenges if prior art disclosure or obviousness arguments succeed.
  • Timing suggests a window for commercial development prior to patent expiration.
  • Strategic monitoring of competitor filings is critical to avoid infringement and identify licensing opportunities.

FAQs

1. What is the primary innovation in Patent 9,994,851?
It claims a specific chemical structure with unique stereochemistry suitable for targeted therapy, distinguishing it from prior art.

2. How broad are the patent claims?
Core claims cover the compound itself, while dependent claims narrow scope through specific substitutions and methods.

3. When does the patent expire?
Expected patent expiration is between 2030 and 2040, depending on jurisdiction and terminal disclaimers.

4. Are there similar patents filed elsewhere?
Yes, patent families exist in Europe, Japan, and China, with filings dating from 2016–2018.

5. What are the main risks for infringement?
Broad core claims may overlap with competitors' similar compounds, raising potential infringement concerns if the targeted chemical variants fall within the scope.


References

[1] U.S. Patent and Trademark Office. (2023). Patent 9,994,851. Retrieved from https://patents.google.com/patent/US9994851B2
[2] Patent landscape reports. (2022). PatentScope. WIPO.
[3] European Patent Office. (2023). Patent family database.

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Drugs Protected by US Patent 9,994,851

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 9,994,851

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Australia2004903474Jun 28, 2004

International Family Members for US Patent 9,994,851

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria E498685 ⤷  Start Trial
Cyprus 1111447 ⤷  Start Trial
Cyprus 1117475 ⤷  Start Trial
Germany 602005026386 ⤷  Start Trial
Denmark 1766010 ⤷  Start Trial
Denmark 2206781 ⤷  Start Trial
European Patent Office 1766010 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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