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Last Updated: July 29, 2021

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Details for Patent: 9,884,094


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Summary for Patent: 9,884,094
Title:Method of treating diabetes mellitus
Abstract: A combination comprising at least a first insulin-like compound and a second insulin-like compound for treating a condition or a disease in a subject in need thereof where administration of insulin would be of benefit to said subject is described. The combination is administered in an amount to achieve a beneficial glycaemic control in said subject as determined by the levels of HbA.sub.1c in said subject after administration of said combination at the largest meal of the day for said subject; wherein said beneficial glycaemic control by said combination is superior to any glycaemic control achieved by an equivalent dose of IGlar in said subject as determined by the levels of HbA.sub.1c in said subject after administration of IGlar for said subject and/or wherein said beneficial glycaemic control by said combination comprises decreasing the levels of HbA.sub.1c in said subject to about 7 or less after administration of said combination at the largest meal of the day; wherein said first insulin-like compound is longer acting than the second insulin-like compound; wherein said combination is administered at the largest meal of the day for said subject; wherein said first insulin-like compound is at least a long acting insulin, preferably an ultra long acting insulin; wherein said first insulin-like compound is a derivative of a naturally occurring insulin or is an insulin analog; and wherein said first insulin-like compound has a side chain attached to the a-amino group of the N-terminal amino acid residue of the B chain or to the .epsilon.-amino group of a Lys residue present in the B chain of the parent insulin, the side chain being of the general formula (I): --W--X--Y--Z.
Inventor(s): Johansen; Thue (Koebenhavn, DK), Mersebach; Henriette (Hellerup, DK), Axelsen; Mads (Virum, DK), Lange; Martin (Bagsvaerd, DK)
Assignee: Novo Nordisk A/S (Bagsvaerd, DK)
Application Number:14/398,018
Patent Claim Types:
see list of patent claims
Use; Formulation;

Drugs Protected by US Patent 9,884,094

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 9,884,094

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
12166251May 1, 2012
12166252May 1, 2012
PCT Information
PCT FiledMay 01, 2013PCT Application Number:PCT/EP2013/059073
PCT Publication Date:November 07, 2013PCT Publication Number: WO2013/164375

International Family Members for US Patent 9,884,094

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2013255880 ⤷  Try it Free
Brazil 112014026442 ⤷  Try it Free
Canada 2872083 ⤷  Try it Free
European Patent Office 2844274 ⤷  Try it Free
Spain 2724731 ⤷  Try it Free
Japan 2015517458 ⤷  Try it Free
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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