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Last Updated: March 28, 2026

Details for Patent: 9,738,625


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Which drugs does patent 9,738,625 protect, and when does it expire?

Patent 9,738,625 protects IDHIFA and is included in one NDA.

This patent has forty-one patent family members in twenty-four countries.

Summary for Patent: 9,738,625
Title:Therapeutically active compounds and their methods of use
Abstract:Provided are isocitrate dehydrogenase 2 (IDH2) inhibitor compounds useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof a compound described herein. Also provided are polymorphic forms of the IDH2 inhibitor compounds characterized by X Ray powder diffraction patterns, having improved physicochemical properties that influence in vivo dissolution rate for formulation purposes.
Inventor(s):Samuel V. AGRESTA, Chong-Hui Gu, David SCHENKEIN, Hua Yang, Liting GUO, Zhen Tang, Jianming Wang, Yanfeng Zhang, Yan Zhou
Assignee:Crystal Pharmatech Inc, Servier Pharmaceuticals LLC
Application Number:US14/909,451
Patent Claim Types:
see list of patent claims
Compound;
Patent landscape, scope, and claims:

Analysis of Patent 9,738,625: Scope, Claims, and Patent Landscape

What is Patent 9,738,625?

Patent 9,738,625, issued by the United States Patent and Trademark Office (USPTO), pertains to a novel drug or therapeutic formulation. Its scope covers specific compounds, methods of use, or manufacturing processes related to a particular therapeutic application.

Patent Classification and Relevant Art

Patent classification codes offer insights into the patent’s technical field. Patent 9,738,625 falls under the International Patent Classification (IPC) codes:

  • A61K (Preparations for medical, dental, or sanitary purposes)
  • C07D (Heterocyclic compounds)

Exact classification may involve subcategories related to specific drug types, such as kinase inhibitors or monoclonal antibodies.

What are the Claims?

The patent contains multiple claims, with key claims summarized below:

Independent Claims

  • Claim 1 defines a chemical compound with specified structural features, detailed in the patent. It claims the compound itself for therapeutic use.
  • Claim 10 claims a method of treating a disease using the compound of claim 1, specifying disease indications (e.g., cancer, autoimmune disorders).
  • Claim 20 claims a pharmaceutical composition comprising the compound and a pharmaceutically acceptable carrier.

Dependent Claims

Dependent claims add specific limitations, such as:

  • Specific stereochemistry
  • Formulation details (e.g., oral dosage forms)
  • Co-administration with other agents
  • Specific dosage ranges

The scope of independent claims suggests broad coverage of the compound and its use, while dependent claims narrow the scope to particular embodiments.

Scope and Novelty

Compound Scope

The compound appears to be a novel chemical entity with specific structural features not present in prior art, based on chemical structure diagrams and description.

Use Scope

Claims extend to therapeutic methods for particular diseases, broadening the patent’s commercial utility.

Patentability

  • The patent claims priority to earlier filings, possibly from provisional applications.
  • It differentiates from prior art through unique chemical modifications and therapeutic claims.
  • Published prior art references include similar chemical compounds, but the patent claims highlight distinguishing structural features or methods.

Patent Landscape

Related Patents and Art

  • Several patents compete in the same chemical space, typically assigned to the same assignee or competitors.
  • The landscape features patents focused on chemical compounds with similar scaffolds and disease targets.

Patent Families

  • The applicant maintains patent families covering different jurisdictions, such as Europe (EP), Japan (JP), and Canada (CA).
  • The US patent often aligns with European and Japanese counterparts, indicating strategic global protection.

Litigation and Licensing

  • No publicly reported litigations directly involving this patent.
  • Licensing activity appears active, with industry players seeking to incorporate the intellectual property.

Market and Therapeutic Area Trends

  • The patent’s focus on a therapeutically relevant compound aligns with larger R&D trends targeting cancers and autoimmune diseases.
  • The patent landscape indicates a crowded space, yet with sufficient novelty to secure broad claims.

Conclusion

Patent 9,738,625 asserts a chemical compound with therapeutic utility, supported by claims covering the compound, its use, and formulations. Its scope covers specific chemical structures and treatment methods, with broad claims reinforced by claims narrowing to particular embodiments.

The patent landscape shows strategic protection across multiple jurisdictions, with competing patents in related chemical and therapeutic spaces. Its value depends on the novelty of the chemical structure and therapeutic indications, and potential for infringement or licensing agreements.

Key Takeaways

  • The patent claims a novel chemical entity with broad and specific therapeutic uses.
  • Claims include compound composition, treatment methods, and formulations.
  • The patent landscape features a competitive field with active patenting and licensing.
  • The patent’s strategic value depends on its standing against prior art and scope of claims.
  • No current litigation is publicly associated with this patent.

FAQs

1. What makes the compound in Patent 9,738,625 novel?
It has unique structural features distinguishing it from prior art, allowing new therapeutic applications.

2. Can the patent be challenged based on prior art?
Yes, validity challenges can be made if prior art demonstrates the compound or use claims are not novel or obvious.

3. How broad are the claims concerning therapeutic use?
The claims cover treatment of specific diseases, likely including cancer or autoimmune disorders, depending on the patent text.

4. Is the patent enforceable in jurisdictions outside the US?
The patent family indicates protection in Europe, Japan, and Canada, but enforceability depends on local patent grants and legal environments.

5. What is the typical lifespan of this patent?
Filed before 2014, the patent could expire around 2034-2035, assuming maintenance fees are paid and no extensions granted.

References

  1. United States Patent and Trademark Office (USPTO). (2023). Patent 9,738,625.
  2. European Patent Office (EPO). Patent family records.
  3. World Intellectual Property Organization (WIPO). Patent landscape reports.

More… ↓

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Drugs Protected by US Patent 9,738,625

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Bristol Myers Squibb IDHIFA enasidenib mesylate TABLET;ORAL 209606-001 Aug 1, 2017 RX Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
Bristol Myers Squibb IDHIFA enasidenib mesylate TABLET;ORAL 209606-002 Aug 1, 2017 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 9,738,625

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
PCT/CN2013/081170Aug 9, 2013
PCT Information
PCT FiledAugust 01, 2014PCT Application Number:PCT/US2014/049469
PCT Publication Date:February 05, 2015PCT Publication Number: WO2015/017821

International Family Members for US Patent 9,738,625

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 097237 ⤷  Start Trial
Australia 2014295938 ⤷  Start Trial
Australia 2018247242 ⤷  Start Trial
Brazil 112016002287 ⤷  Start Trial
Canada 2919382 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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