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Last Updated: May 1, 2024

Details for Patent: 9,604,948


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Summary for Patent: 9,604,948
Title:Process for preparing substituted 5-fluoro-1H-pyrazolopyridines
Abstract: The present application relates to a novel and efficient process for preparing novel substituted 5-fluoro-1H-pyrazolopyridines of the formula (VI) ##STR00001## which are suitable as an intermediate for production of medicaments and for production of medicaments for treatment and/or prophylaxis of cardiovascular disorders. More particularly, the 5-fluoro-1H-pyrazolopyridines of the formula (VI) are suitable for preparation of the compound of the formula (I) ##STR00002## which serves for production of medicaments, for production of medicaments for treatment and/or prophylaxis of cardiovascular disorders.
Inventor(s): Fey; Peter (Wuppertal, DE), Grunenberg; Alfons (Wuppertal, DE), Bierer; Donald (Haan, DE)
Assignee: ADVERIO PHARMA GMBH (Schoenefeld, DE)
Application Number:14/796,703
Patent Claim Types:
see list of patent claims
Use; Composition; Compound; Process;

Drugs Protected by US Patent 9,604,948

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Merck Sharp Dohme VERQUVO vericiguat TABLET;ORAL 214377-001 Jan 19, 2021 RX Yes No ⤷  Try a Trial ⤷  Try a Trial Y Y REDUCING THE RISK OF CARDIOVASCULAR DEATH AND HEART FAILURE (HF) HOSPITALIZATION FOLLOWING A HOSPITALIZATION FOR HF OR NEED FOR OUTPATIENT IV DIURETICS, IN ADULTS WITH SYMPTOMATIC CHRONIC HF AND EJECTION FRACTION LESS THAN 45% ⤷  Try a Trial
Merck Sharp Dohme VERQUVO vericiguat TABLET;ORAL 214377-002 Jan 19, 2021 RX Yes No ⤷  Try a Trial ⤷  Try a Trial Y Y REDUCING THE RISK OF CARDIOVASCULAR DEATH AND HEART FAILURE (HF) HOSPITALIZATION FOLLOWING A HOSPITALIZATION FOR HF OR NEED FOR OUTPATIENT IV DIURETICS, IN ADULTS WITH SYMPTOMATIC CHRONIC HF AND EJECTION FRACTION LESS THAN 45% ⤷  Try a Trial
Merck Sharp Dohme VERQUVO vericiguat TABLET;ORAL 214377-003 Jan 19, 2021 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y REDUCING THE RISK OF CARDIOVASCULAR DEATH AND HEART FAILURE (HF) HOSPITALIZATION FOLLOWING A HOSPITALIZATION FOR HF OR NEED FOR OUTPATIENT IV DIURETICS, IN ADULTS WITH SYMPTOMATIC CHRONIC HF AND EJECTION FRACTION LESS THAN 45% ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 9,604,948

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
11190789Nov 25, 2011
11192301Dec 7, 2011

International Family Members for US Patent 9,604,948

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
African Regional IP Organization (ARIPO) 3898 ⤷  Try a Trial
Argentina 088983 ⤷  Try a Trial
Argentina 125027 ⤷  Try a Trial
Australia 2012342547 ⤷  Try a Trial
Australia 2017254916 ⤷  Try a Trial
Australia 2019202123 ⤷  Try a Trial
Brazil 112014012414 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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