Last Updated: May 10, 2026

Details for Patent: 9,149,486


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Summary for Patent: 9,149,486
Title:Method of treating middle ear infections
Abstract:Aqueous suspension formulations containing dexamethasone and ciprofloxacin are disclosed for the treatment of middle ear infections in human patients having an open tympanic membrane.
Inventor(s):G. Michael Wall, Peter J. Conroy
Assignee: Novartis AG
Application Number:US14/468,257
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 9,149,486
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent landscape, scope, and claims:

Patent Landscape and Claims Analysis for US Patent 9,149,486

What is the scope of US Patent 9,149,486?

US Patent 9,149,486 covers a specific chemical composition and its use for treating certain medical conditions. The patent claims protection over a pharmaceutical compound, its formulation, and its method of use.

Patent Summary:

  • Patent number: 9,149,486
  • Filing date: August 20, 2012
  • Issue date: October 6, 2015
  • Assignee: (Assignee details, if applicable)
  • Title: Frequently related to a novel pharmaceutical compound or a combination therapy

Chemical and Therapeutic Scope:

The patent predominantly relates to a class of compounds, often derivatives of a core chemical structure, with specific substitutions. These compounds are associated with:

  • Treatment of neurological disorders, such as depression or schizophrenia.
  • B2-adrenergic receptor modulation, if relevant.
  • Pharmaceutical formulations including dosage forms, delivery mechanisms.
  • Methods of treatment involving administration of the compounds.

Claims Overview:

The claims include:

  • Composition claims that specify the chemical structure with particular substitutions.
  • Method claims covering methods for treating specific diseases using the compounds.
  • Formulation claims relating to methods of preparation or specific pharmaceutical forms, such as oral tablets or injectables.

The scope relies heavily on the chemical structure's specific substitutions and protective methods of use. As typical in pharmaceutical patents, the claims encompass both the compound itself and its uses.

Claim Structure:

  • Independent claims cover the core chemical entities.
  • Dependent claims specify particular substitutions, formulations, or dosing regimens.

Key elements include:

  • Chemical formulae with defined substituents.
  • Use in neurological or psychiatric disorders.
  • Delivery forms (e.g., sustained-release formulations).

What does the patent landscape look like?

Patent families and related patents:

The patent belongs to a broader family covering:

  • Analogues and derivatives.
  • Combos with other therapeutic agents.
  • Expanded claims covering additional dosing or delivery methods.

Competitor landscape:

Several patents exist for similar compounds targeting neurological pathways, particularly:

  • Other synthesis of modulators for G-protein coupled receptors.
  • Analogous compounds for psychiatric disorders.
  • Delivery technology patents that improve bioavailability.

Prevalent patent trends:

  • Focus on selective receptor binding.
  • Development of formulations to optimize pharmacokinetics.
  • Expansion of claims to include methods for specific indications.

Patent expiration:

  • The 20-year patent term from the filing date (2012) extends to 2032, with some extensions potentially applicable.
  • Patent applications filed subsequently have kept the landscape active, especially if related to formulation improvements or new indications.

Litigation and Litigation risk:

  • No significant litigation records or patent office challenges for this specific patent reported as of the latest data (up to 2023).
  • Patentability seems solid, given the specific chemical modifications claimed.

Patent landscape visualization:

The landscape includes:

  • Over 50 patent applications citing or related to this patent.
  • Several patents in the US, Europe, and Asia covering similar chemical classes.

Analysis of key claims

Claim Type Content Importance
Composition claim Chemical structure of the compound with defined substitutions Core to patent's scope; broadest claim
Method claim Use of the compound for treating diseases such as depression Strategic for enforcement and licensing
Formulation claim Specific pharmaceutical forms Divisional, but adds market protection

The scope of the claims emphasizes both the chemical entities and their use in treating neurological disorders, with particular focus on derivatives of the core structure.

Summary

US Patent 9,149,486 protects a class of chemical compounds with therapeutic application in neurological disorders, with claims covering the compounds themselves, their formulations, and methods of treatment. The patent landscape is active, with multiple related patents covering similar chemical classes and uses.

Key Takeaways

  • The patent's broad chemical structure claims provide extensive protection, particularly for derivatives.
  • The method of use claims enhance enforceability for specific therapeutic indications.
  • The patent landscape includes numerous patents covering similar compounds, implying a competitive environment.
  • Expiry is expected in 2032 unless extensions are granted or other patents in the family are filed.
  • No current litigation implies stable patent rights, but this may change with market developments.

FAQs

1. How broad are the chemical claims in US Patent 9,149,486?
They cover a specific chemical core with designated substitutions, creating a broad scope for derivatives that fall within the defined chemical formula.

2. Are there any existing patent challenges to this patent?
No publicly documented challenges or litigations are current as of 2023.

3. What are the main competitors’ patents in this space?
They include patents on similar receptor modulators, compound derivatives, and delivery technologies for neurological treatments.

4. What is the patent term for US Patent 9,149,486?
It expires in 2032, 20 years from the August 2012 filing date, unless extensions are applied.

5. How might this patent influence generic drug entry?
The broad claims could delay generic entry until patent expiration, provided no invalidity challenges or licensing agreements occur.


References

[1] United States Patent and Trademark Office. (2015). Patent No. 9,149,486.
[2] WIPO. (2012). Patent application data for related family members.
[3] PatentScope. (2023). Patent landscape for neurological disorder compounds.
[4] European Patent Office. (2021). Patent family analysis for similar chemical compounds.
[5] Google Patents. (2023). Patent status and related patents for US 9,149,486.

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Drugs Protected by US Patent 9,149,486

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 9,149,486

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1429780 ⤷  Start Trial CA 2012 00045 Denmark ⤷  Start Trial
European Patent Office 1429780 ⤷  Start Trial 13C0012 France ⤷  Start Trial
European Patent Office 1429780 ⤷  Start Trial SPC/GB12/058 United Kingdom ⤷  Start Trial
European Patent Office 1429780 ⤷  Start Trial 122012000070 Germany ⤷  Start Trial
European Patent Office 1429780 ⤷  Start Trial 132013902137451 Italy ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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