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Last Updated: April 16, 2024

Details for Patent: 9,133,461


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Which drugs does patent 9,133,461 protect, and when does it expire?

Patent 9,133,461 protects GIVLAARI and is included in one NDA.

This patent has fifty-four patent family members in twenty-seven countries.

Summary for Patent: 9,133,461
Title:Compositions and methods for inhibiting expression of the ALAS1 gene
Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ALAS1 gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of ALAS1.
Inventor(s): Bettencourt; Brian (Groton, MA), Fitzgerald; Kevin (Brookline, MA), Querbes; William (Cambridge, MA), Desnick; Robert J. (New York, NY), Yasuda; Makiko (New York, NY)
Assignee: Alnylam Pharmaceuticals, Inc. (Cambridge, MA) Icahn School of Medicine at Mount Sinai (New York, NY)
Application Number:13/835,613
Patent Claim Types:
see list of patent claims
Use; Composition; Formulation; Compound;

Drugs Protected by US Patent 9,133,461

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alnylam Pharms Inc GIVLAARI givosiran sodium SOLUTION;SUBCUTANEOUS 212194-001 Nov 20, 2019 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y TREATMENT OF ACUTE HEPATIC PORPHYRIA ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 9,133,461

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 090641 ⤷  Try a Trial
Australia 2013245949 ⤷  Try a Trial
Australia 2018203098 ⤷  Try a Trial
Australia 2020202970 ⤷  Try a Trial
Australia 2024200975 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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