Last Updated: October 1, 2026

Details for Patent: 9,018,210


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Which drugs does patent 9,018,210 protect, and when does it expire?

Patent 9,018,210 protects OXBRYTA and is included in two NDAs.

This patent has eighty-three patent family members in thirty-two countries.

Summary for Patent: 9,018,210
Title:Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation
Abstract:Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
Inventor(s):Brian Metcalf, Chihyuan Chuang
Assignee: TANDEM SCIENCES Inc , Global Blood Therapeutics Inc , University of California San Diego UCSD
Application Number:US13/730,674
Patent Claim Types:
see list of patent claims
Composition; Compound;

Drugs Protected by US Patent 9,018,210

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Global Blood Theraps OXBRYTA voxelotor TABLET, FOR SUSPENSION;ORAL 216157-001 Dec 17, 2021 DISCN Yes No ⤷  Start Trial ⤷  Start Trial Y Y ⤷  Start Trial
Global Blood Theraps OXBRYTA voxelotor TABLET;ORAL 213137-002 Oct 14, 2022 DISCN Yes No ⤷  Start Trial ⤷  Start Trial Y Y ⤷  Start Trial
Global Blood Theraps OXBRYTA voxelotor TABLET;ORAL 213137-001 Nov 25, 2019 DISCN Yes No ⤷  Start Trial ⤷  Start Trial Y Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 9,018,210

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 2797416 ⤷  Start Trial 301191 Netherlands ⤷  Start Trial
European Patent Office 2797416 ⤷  Start Trial CA 2022 00032 Denmark ⤷  Start Trial
European Patent Office 2797416 ⤷  Start Trial PA2022517 Lithuania ⤷  Start Trial
European Patent Office 2797416 ⤷  Start Trial 122022000052 Germany ⤷  Start Trial
European Patent Office 2797416 ⤷  Start Trial LUC00276 Luxembourg ⤷  Start Trial
European Patent Office 2797416 ⤷  Start Trial 2022C/537 Belgium ⤷  Start Trial
European Patent Office 2797416 ⤷  Start Trial 32/2022 Austria ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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