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Last Updated: August 3, 2021

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Details for Patent: 8,980,853

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Which drugs does patent 8,980,853 protect, and when does it expire?

Patent 8,980,853 protects SPINRAZA and is included in one NDA.

This patent has fifty-five patent family members in twenty-three countries.

Summary for Patent: 8,980,853
Title:Compositions and methods for modulation of SMN2 splicing in a subject
Abstract: Disclosed herein are compounds, compositions and methods for modulating splicing of SMN2 mRNA in a subject. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders, including spinal muscular atrophy.
Inventor(s): Bennett; C. Frank (Carlsbad, CA), Hung; Gene (San Diego, CA), Rigo; Frank (Carlsbad, CA), Krainer; Adrian R. (Huntington Square, NY), Hua; Yimin (Jericho, NY), Passini; Marco A. (Shrewsbury, MA), Shihabuddin; Lamya (Brighton, MA), Cheng; Seng H. (Natick, MA), Klinger; Katherine W. (Sudbury, MA)
Assignee: Isis Pharmaceuticals, Inc. (Carlsbad, CA) Cold Spring Harbor Laboratory (Cold Spring Harbor, NY)
Application Number:13/380,021
Patent Claim Types:
see list of patent claims

Drugs Protected by US Patent 8,980,853

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Biogen Idec SPINRAZA nusinersen sodium SOLUTION;INTRATHECAL 209531-001 Dec 23, 2016 RX Yes Yes ⤷  Try it Free ⤷  Try it Free TREATMENT OF INFANTILE-ONSET SPINAL MUSCULAR ATROPHY ⤷  Try it Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,980,853

PCT Information
PCT FiledJune 17, 2010PCT Application Number:PCT/US2010/039077
PCT Publication Date:December 23, 2010PCT Publication Number: WO2010/148249

International Family Members for US Patent 8,980,853

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2010262862 ⤷  Try it Free
Australia 2016200344 ⤷  Try it Free
Canada 2765396 ⤷  Try it Free
China 102665731 ⤷  Try it Free
China 106983768 ⤷  Try it Free
Cyprus 1120807 ⤷  Try it Free
Denmark 3305302 ⤷  Try it Free
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

Express Scripts
Harvard Business School
Johnson and Johnson

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