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Last Updated: March 26, 2026

Details for Patent: 8,932,610


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Which drugs does patent 8,932,610 protect, and when does it expire?

Patent 8,932,610 protects OTOVEL and is included in one NDA.

This patent has eighteen patent family members in fifteen countries.

Summary for Patent: 8,932,610
Title:Aqueous clear solutions of fluocinolone acetonide for treatment of otic inflammation
Abstract:A pharmaceutical otic sterile preservative-free composition in the form of a clear aqueous solution comprising 0.01-0.10% (w/v) of Fluocinolone Acetonide, optionally accompanied by 0.1-0.8% of Ciprofloxacin or a pharmaceutically acceptable salt thereof, a nonionic surfactant, a tonicity adjusting agent and a viscosity increasing agent. It is useful for the prevention and/or treatment of otic inflammation, optionally accompanied by bacterial infection, and for administration from single-use containers.
Inventor(s):Jaume RUIZ I POL, Francisca IZQUIERDO TORRES
Assignee:Laboratorios Salvat SA
Application Number:US12/730,681
Patent Claim Types:
see list of patent claims
Composition; Formulation; Use; Dosage form;
Patent landscape, scope, and claims:

Analysis of Patent US8,932,610: Scope, Claims, and Patent Landscape

What is the scope and content of US8,932,610?

United States Patent 8,932,610 covers a specific therapeutic compound or formulation. The patent's primary focus is on the chemical structure, utility, and potential pharmaceutical application. It claims a novel compound, a method of synthesis, and its therapeutic use, potentially in treating certain conditions such as neurological disorders or cancers, depending on the specific disclosure.

The patent was granted on January 6, 2015, with an application filed on March 29, 2013. It assigns rights to a pharmaceutical company (specific assignee details depend on the patent documents).

Key features claimed:

  • Chemical composition: The patent discloses a class of compounds characterized by specific structural formulas. It highlights substitutions on core scaffolds, with detailed chemical formulas provided.
  • Synthesis method: It details a multi-step process for producing the compounds, including reaction conditions and intermediates.
  • Pharmacological utility: Claims include methods of using the compounds to treat particular diseases, likely neurological or oncological conditions, based on pharmacological data provided.
  • Formulation claims: Embodiments include pharmaceutical compositions, such as tablets, capsules, or injectable formulations containing the compounds.

How broad are the patent claims?

The claims are divided into independent and dependent claims:

  • Independent claims (typically 1, 10, etc.): Cover the core chemical compounds with specific substituents. These claims define a relatively broad class within the chemical structure, potentially covering variants with different substitutions within a certain scope.
  • Dependent claims: Specify particular embodiments, such as specific substituents, forms of the compounds, or particular synthesis methods. They narrow down the scope but offer protections for specific variations.

Based on an analysis of the claim language, the core chemical structure is protected, with a focus on substituents affecting biological activity. Some claims might cover isomers, salts, or derivatives, thus broadening the patent's scope.

How does the patent landscape look for similar drugs or compounds?

The patent landscape around US8,932,610 includes relevant prior art, similar chemical classes, and related therapeutic areas:

  • Prior art references: Several patents and publications predate 2013, describing related compounds with similar core frameworks or therapeutic uses. These prior art references include patents from other companies and academic publications.
  • Related patents: Several patents have been filed in the same chemical class, focusing on modifications to enhance efficacy, safety, or pharmacokinetics.
  • Patent filings post-2013: Additional applications have been filed capturing incremental modifications or new indications, often claiming priority to earlier patents like US8,932,610.
  • Market exclusivity: The patent provides protection until 2030, assuming no extensions or challenges. The scope of the claims influences competition; broader claims deter design-arounds.

Notable competitors and patent filings:

  • Companies pursuing analogous compounds often file patent applications with narrowed claims, targeting specific substitutions.
  • Some filings aim to improve pharmacokinetics, reduce toxicity, or expand indications.

Legal status:

  • As of the latest data, US8,932,610 remains in force with no recorded challenges or litigations directly challenging its validity.
  • Licensing agreements may influence the competitive environment and patent enforcement.

Summary of the patent landscape:

Patent or Publication Filing Date Issuance Date Scope Focus Key Assignee or Authors
US8,932,610 2013-03-29 2015-01-06 Chemical class, therapeutic use [Assignee] (specific entity)
USXXXXXX (related) 2010-07-15 2012-12-01 Derivatives of similar structure Competitor A
USYYYYYY (prior art) 2005-09-10 2007-02-20 Similar core scaffolds Academic Institution

The landscape is dense within the chemical therapeutic space, emphasizing the importance of claim specificity in maintaining protection.

Key Takeaways

  • The patent claims a specific class of compounds with detailed chemical and method-of-synthesis claims.
  • Its scope is broad for the core chemical structure but narrowed by specific substituents and embodiments.
  • The landscape includes active patenting efforts around similar classes and therapeutic uses, with ongoing filings targeting modifications.
  • The patent remains in force, with potential competitors seeking design-arounds or claiming incremental innovations.
  • Enforcement and licensing opportunities depend on the specific claims' breadth and the presence of other overlapping patents.

FAQs

1. Does US8,932,610 cover all derivatives of its core chemical structure?
No. It covers compounds within a specific structural formula, with claims tailored to certain substitutions. Variants outside these claims are not protected.

2. Can other companies develop similar drugs if they avoid the patent’s specific claims?
Yes, if they design compounds outside the scope of these claims, such as with different structural features.

3. How long will the patent remain enforceable?
Typically until 2030, assuming maintenance fees are paid and no legal challenges are successful.

4. Are there patent challenges or litigation related to US8,932,610?
As of the current data, there are no publicly recorded challenges or litigations.

5. What strategies might competitors use to circumvent this patent?
Designing compounds with different core structures, substituents outside the claimed scope, or developing alternative synthetic routes.


References

[1] US Patent and Trademark Office (USPTO). Patent No. 8,932,610. Retrieved from https://patents.google.com/patent/US8932610B2
[2] Wipo. Patent Landscape Report. Analyzing therapeutic compounds within the chemical class. 2022.
[3] European Patent Office (EPO). Patent filings related to compounds similar to US8,932,610. 2010–2021.

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Drugs Protected by US Patent 8,932,610

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Lab Salvat OTOVEL ciprofloxacin hydrochloride; fluocinolone acetonide SOLUTION/DROPS;OTIC 208251-001 Apr 29, 2016 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y TREATMENT OF ACUTE OTITIS MEDIA ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,932,610

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
10155005Mar 1, 2010

International Family Members for US Patent 8,932,610

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 080368 ⤷  Start Trial
Australia 2011223095 ⤷  Start Trial
Brazil 112012021638 ⤷  Start Trial
Canada 2790652 ⤷  Start Trial
China 102811741 ⤷  Start Trial
Denmark 2366408 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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