Last Updated: August 9, 2026

Details for Patent: 8,927,540


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Summary for Patent: 8,927,540
Title:Pyridazinone derivatives
Abstract:Compounds of the formula (I), in which R1, R2, R3, R4, R4′, have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors.
Inventor(s):Dieter Dorsch, Frank Stieber, Oliver Schadt, Andree Blaukat
Assignee: Merck Patent GmbH
Application Number:US13/785,580
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 8,927,540

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Emd Serono Inc TEPMETKO tepotinib hydrochloride TABLET;ORAL 214096-001 Feb 3, 2021 RX Yes Yes 8,927,540 ⤷  Start Trial TREATING A SOLID TUMOR, INCLUDING LUNG CANCER, HAVING A MET KINASE ALTERATION(S) BY ADMINISTERING AN EFFECTIVE AMOUNT OF TEPOTINIB ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,927,540

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Germany10 2007 032 507Jul 12, 2007

International Family Members for US Patent 8,927,540

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 2164843 ⤷  Start Trial C02164843/01 Switzerland ⤷  Start Trial
European Patent Office 2164843 ⤷  Start Trial 301176 Netherlands ⤷  Start Trial
European Patent Office 2164843 ⤷  Start Trial PA2022009 Lithuania ⤷  Start Trial
European Patent Office 2164843 ⤷  Start Trial 2022C/519 Belgium ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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