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Last Updated: July 30, 2021

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Details for Patent: 8,859,562


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Summary for Patent: 8,859,562
Title:Use of RNAI inhibiting PARP activity for the manufacture of a medicament for the treatment of cancer
Abstract: The present invention relates to the use of an agent that inhibits the activity of an enzyme that mediates repair of a DNA strand break in the manufacture of a medicament for the treatment of diseases caused by a defect in a gene that mediates homologous recombination.
Inventor(s): Helleday; Thomas (Stockholm, SE)
Assignee: The University of Sheffield (Sheffield, GB)
Application Number:10/555,507
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 8,859,562

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Astrazeneca LYNPARZA olaparib CAPSULE;ORAL 206162-001 Dec 19, 2014 DISCN Yes No ⤷  Free Forever Trial ⤷  Free Forever Trial TREATMENT OF BRCA MUTATED OVARIAN CANCER USING PARP INHIBITOR ⤷  Free Forever Trial
Glaxosmithkline ZEJULA niraparib tosylate CAPSULE;ORAL 208447-001 Mar 27, 2017 RX Yes Yes ⤷  Free Forever Trial ⤷  Free Forever Trial A METHOD OF TREATMENT OF ADVANCED OVARIAN, FALLOPIAN TUBE, OR PRIMARY PERITONEAL CANCER ASSOCIATED WITH HOMOLOGOUS RECOMBINATION DEFICIENCY (HRD) POSITIVE STATUS ⤷  Free Forever Trial
Astrazeneca LYNPARZA olaparib TABLET;ORAL 208558-001 Aug 17, 2017 RX Yes No ⤷  Free Forever Trial ⤷  Free Forever Trial TREATMENT OF DELETERIOUS OR SUSPECTED DELETERIOUS GERMLINE BRCA-MUTATED ADVANCED OVARIAN CANCER WHO HAVE BEEN TREATED WITH THREE OR MORE PRIOR LINES OF CHEMOTHERAPY ⤷  Free Forever Trial
Astrazeneca LYNPARZA olaparib TABLET;ORAL 208558-001 Aug 17, 2017 RX Yes No ⤷  Free Forever Trial ⤷  Free Forever Trial MAINTENANCE TREATMENT OF RECURRENT EPITHELIAL OVARIAN, FALLOPIAN TUBE OR PRIMARY PERITONEAL CANCER, WHO ARE IN A COMPLETE OR PARTIAL RESPONSE TO PLATINUM-BASED CHEMOTHERAPY ⤷  Free Forever Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,859,562

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom0317466.1Jul 25, 2003
PCT Information
PCT FiledJuly 23, 2004PCT Application Number:PCT/GB2004/003235
PCT Publication Date:February 10, 2005PCT Publication Number: WO2005/012524

International Family Members for US Patent 8,859,562

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 454893 ⤷  Free Forever Trial
Austria 516353 ⤷  Free Forever Trial
Australia 2004261462 ⤷  Free Forever Trial
Australia 2004261779 ⤷  Free Forever Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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