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Serving leading biopharmaceutical companies globally:

Merck
Citi
Chinese Patent Office
Cantor Fitzgerald
Mallinckrodt
McKesson
McKinsey
Dow
AstraZeneca
Express Scripts

Generated: December 11, 2017

DrugPatentWatch Database Preview

Details for Patent: 8,859,562

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Which drugs does patent 8,859,562 protect, and when does it expire?


Patent 8,859,562 protects LYNPARZA and RUBRACA and is included in three NDAs.

This patent has fifty-two patent family members in twenty-three countries.

Summary for Patent: 8,859,562

Title:Use of RNAI inhibiting PARP activity for the manufacture of a medicament for the treatment of cancer
Abstract: The present invention relates to the use of an agent that inhibits the activity of an enzyme that mediates repair of a DNA strand break in the manufacture of a medicament for the treatment of diseases caused by a defect in a gene that mediates homologous recombination.
Inventor(s): Helleday; Thomas (Stockholm, SE)
Assignee: The University of Sheffield (Sheffield, GB)
Application Number:10/555,507
Patent Claim Types:
see list of patent claims
Use;

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Patent Submitted Product Substance Delist Req. Patented / Exclusive Use
Astrazeneca PharmsLYNPARZAolaparibCAPSULE;ORAL206162-001Dec 19, 2014RXYesYes► Subscribe► Subscribe► SubscribeTREATMENT OF BRCA MUTATED OVARIAN CANCER USING PARP INHIBITOR
Astrazeneca PharmsLYNPARZAolaparibTABLET;ORAL208558-001Aug 17, 2017RXYesNo► Subscribe► Subscribe► Subscribe
Astrazeneca PharmsLYNPARZAolaparibTABLET;ORAL208558-002Aug 17, 2017RXYesYes► Subscribe► Subscribe► Subscribe
Clovis Oncology IncRUBRACArucaparib camsylateTABLET;ORAL209115-001Dec 19, 2016RXYesNo► Subscribe► Subscribe► Subscribe
Clovis Oncology IncRUBRACArucaparib camsylateTABLET;ORAL209115-003May 1, 2017RXYesNo► Subscribe► Subscribe► Subscribe
Clovis Oncology IncRUBRACArucaparib camsylateTABLET;ORAL209115-002Dec 19, 2016RXYesYes► Subscribe► Subscribe► Subscribe
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Foreign Priority and PCT Information for Patent: 8,859,562

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom0317466.1Jul 25, 2003
PCT Information
PCT FiledJuly 23, 2004PCT Application Number:PCT/GB2004/003235
PCT Publication Date:February 10, 2005PCT Publication Number: WO2005/012524

Non-Orange Book Patents for Patent: 8,859,562

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
7,351,701Therapeutic compounds► Subscribe
7,531,530Therapeutic compounds► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Because of the complexity of determining patent expiration dates it is advisable to have patent counsel verify freedom to operate.

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International Patent Family for Patent: 8,859,562

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria454893► Subscribe
Austria516353► Subscribe
Australia2004261462► Subscribe
Australia2004261779► Subscribe
BrazilPI0412899► Subscribe
BrazilPI0412909► Subscribe
Canada2533332► Subscribe
Canada2533423► Subscribe
China102935230► Subscribe
China1856313► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Mallinckrodt
Johnson and Johnson
Fish and Richardson
Express Scripts
McKesson
Deloitte
Novartis
Baxter
Daiichi Sankyo
Cipla

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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