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Serving hundreds of leading biopharmaceutical companies globally:

Moodys
McKesson
Colorcon
Queensland Health
US Army
Healthtrust
Mallinckrodt
Harvard Business School
Julphar

Generated: May 20, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,834,921

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Which drugs does patent 8,834,921 protect, and when does it expire?

Patent 8,834,921 protects EXPAREL and is included in one NDA.

This patent has twenty patent family members in fifteen countries.
Summary for Patent: 8,834,921
Title:Sustained-release liposomal anesthetic compositions
Abstract: The invention provides a method for obtaining local anesthetics encapsulated in liposomes, such as multi vesicular liposomes, with high encapsulation efficiency and slow release in vivo. When the encapsulated anesthetic is administered as a single intracutaneous dose, the duration of anesthesia and half-life of the drug at the local injection site is increased as compared to injection of unencapsulated anesthetic. The maximum tolerated dose of the encapsulated anesthetic is also markedly increased in the liposomal formulation over injection of unencapsulated anesthetic. These results show that the liposomal formulation of local anesthetic is useful for sustained local infiltration and nerve block anesthesia.
Inventor(s): Kim; Sinil (La Jolla, CA), Kim; Taehee (Carlsbad, CA), Murdande; Sharad (Waterford, CT)
Assignee: Pacira Pharmaceuticals, Inc. (San Diego, CA)
Application Number:13/476,823
Patent Claim Types:
see list of patent claims
Formulation; Compound; Dosage form; Process; Composition; Use;

Drugs Protected by US Patent 8,834,921

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Pacira Pharms Inc EXPAREL bupivacaine INJECTABLE, LIPOSOMAL;INJECTION 022496-001 Oct 28, 2011 RX Yes Yes ➤ Sign Up ➤ Sign Up Y SINGLE-DOSE INFILTRATION INTO THE SURGICAL SITE TO PRODUCE POSTSURGICAL ANALGESIA. ➤ Sign Up
Pacira Pharms Inc EXPAREL bupivacaine INJECTABLE, LIPOSOMAL;INJECTION 022496-002 Oct 28, 2011 RX Yes Yes ➤ Sign Up ➤ Sign Up Y SINGLE-DOSE INFILTRATION INTO THE SURGICAL SITE TO PRODUCE POSTSURGICAL ANALGESIA. ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 8,834,921

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
9,192,575 Sustained-release liposomal anesthetic compositions ➤ Sign Up
6,045,824 Sustained-release liposomal anesthetic compositions ➤ Sign Up
9,205,052 Sustained-release liposomal anesthetic compositions ➤ Sign Up
8,182,835 Sustained-release liposomal anesthetic compositions ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Moodys
Johnson and Johnson
Cerilliant
Cipla
Fish and Richardson
Federal Trade Commission
Covington
US Department of Justice
Cantor Fitzgerald

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