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Last Updated: April 26, 2024

Details for Patent: 8,778,305


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Summary for Patent: 8,778,305
Title:PSMA-binding agents and uses thereof
Abstract: Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis.
Inventor(s): Pomper; Martin (Baltimore, MD), Mease; Ronnie Charles (Fairfax, VA), Chen; Ying (Timonium, MD)
Assignee: The Johns Hopkins University (Baltimore, MD)
Application Number:13/057,044
Patent Claim Types:
see list of patent claims
Use; Compound; Device;

Drugs Protected by US Patent 8,778,305

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Progenics Pharms Inc PYLARIFY piflufolastat f-18 SOLUTION;INTRAVENOUS 214793-001 May 26, 2021 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y METHOD OF POSITRON EMISSION TOMOGRAPHY (PET) IN MEN WITH PROSTATE CANCER ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,778,305

PCT Information
PCT FiledJuly 31, 2009PCT Application Number:PCT/US2009/052456
PCT Publication Date:February 04, 2010PCT Publication Number: WO2010/014933

International Family Members for US Patent 8,778,305

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2009276423 ⤷  Try a Trial
Canada 2732632 ⤷  Try a Trial
Canada 2987744 ⤷  Try a Trial
China 102171187 ⤷  Try a Trial
China 107382846 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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