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Details for Patent: 8,748,413
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Which drugs does patent 8,748,413 protect, and when does it expire?
Patent 8,748,413 protects APADAZ and is included in one NDA.
This patent has thirty-two patent family members in nineteen countries.
Summary for Patent: 8,748,413
| Title: | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof |
| Abstract: | The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. |
| Inventor(s): | Mickle; Travis (Coralville, IA), Guenther; Sven (Coralville, IA), Mickle; Christal (Coralville, IA), Chi; Guochen (Coralville, IA), Kanski; Jaroslaw (Blacksburg, VA), Martin; Andrea K. (Fincastle, VA), Bera; Bindu (Blacksburg, VA) |
| Assignee: | KemPharm, Inc. (Coralville, IA) |
| Application Number: | 13/888,578 |
|
Patent Claim Types: see list of patent claims | Composition; Formulation; Compound; Device; Dosage form; |
Drugs Protected by US Patent 8,748,413
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kvk Tech Inc | APADAZ | acetaminophen; benzhydrocodone hydrochloride | TABLET;ORAL | 208653-002 | Jan 4, 2019 | RX | Yes | No | ➤ Sign Up | ➤ Sign Up | Y | Y | ➤ Sign Up | |||
| Kvk Tech Inc | APADAZ | acetaminophen; benzhydrocodone hydrochloride | TABLET;ORAL | 208653-001 | Feb 23, 2018 | RX | Yes | No | ➤ Sign Up | ➤ Sign Up | Y | Y | ➤ Sign Up | |||
| Kvk Tech Inc | APADAZ | acetaminophen; benzhydrocodone hydrochloride | TABLET;ORAL | 208653-003 | Jan 4, 2019 | RX | Yes | No | ➤ Sign Up | ➤ Sign Up | Y | Y | ➤ Sign Up | |||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,748,413
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Australia | 2010266205 | ➤ Sign Up | |||
| Brazil | 112012000569 | ➤ Sign Up | |||
| Canada | 2766388 | ➤ Sign Up | |||
| China | 102480959 | ➤ Sign Up | |||
| Colombia | 6480991 | ➤ Sign Up | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
