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Last Updated: November 17, 2019

DrugPatentWatch Database Preview

Details for Patent: 8,680,111

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Which drugs does patent 8,680,111 protect, and when does it expire?

Patent 8,680,111 protects LORBRENA and is included in one NDA.

This patent has fifty-one patent family members in forty-three countries.

Summary for Patent: 8,680,111
Title:Macrocyclic derivatives for the treatment of diseases
Abstract: The invention relates to compounds of formula (.PHI.) ##STR00001## as further defined herein and to the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to the uses thereof. The compounds and salts of the present invention inhibit anaplastic lymphoma kinase (ALK) and/or EML4-ALK and are useful for treating or ameliorating abnormal cell proliferative disorders, such as cancer.
Inventor(s): Bailey; Simon (San Diego, CA), Burke; Benjamin Joseph (San Diego, CA), Collins; Michael Raymond (San Diego, CA), Cui; Jingrong Jean (San Diego, CA), Deal; Judith Gail (Wildomar, CA), Hoffman; Robert Louis (San Marcos, CA), Huang; Qinhua (San Diego, CA), Johnson; Ted William (Carlsbad, CA), Kania; Robert Steven (San Diego, CA), Kath; John Charles (La Mesa, CA), Le; Phuong Thi Quy (San Diego, CA), McTigue; Michele Ann (Encinitas, CA), Palmer; Cynthia Louise (La Mesa, CA), Richardson; Paul Francis (San Diego, CA), Sach; Neal William (San Diego, CA)
Assignee: Pfizer Inc. (New York, NY)
Application Number:13/786,106
Patent Claim Types:
see list of patent claims
Composition; Compound;

Drugs Protected by US Patent 8,680,111

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Pfizer Inc LORBRENA lorlatinib TABLET;ORAL 210868-001 Nov 2, 2018 RX Yes No   Start Trial   Start Trial Y Y   Start Trial
Pfizer Inc LORBRENA lorlatinib TABLET;ORAL 210868-002 Nov 2, 2018 RX Yes Yes   Start Trial   Start Trial Y Y   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,680,111

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 090230   Start Trial
Australia 2013229173   Start Trial
Brazil 112014022106   Start Trial
Canada 2863892   Start Trial
Chile 2014002084   Start Trial
China 104169286   Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

Harvard Business School
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McKinsey
Merck
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Medtronic

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