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Last Updated: September 30, 2020

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Details for Patent: 8,653,119

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Summary for Patent: 8,653,119
Title:Methods for treating transthyretin amyloid diseases
Abstract: Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods are disclosed.
Inventor(s): Kelly; Jeffery W. (La Jolla, CA), Powers; Evan T. (La Jolla, CA), Razavi; Hossein (Danbury, CT)
Assignee: The Scripps Research Institute (La Jolla, CA)
Application Number:13/303,060
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 8,653,119

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Foldrx Pharms VYNDAQEL tafamidis meglumine CAPSULE;ORAL 211996-001 May 3, 2019 RX Yes Yes   Start Trial   Start Trial TREATMENT OF THE CARDIOMYOPATHY OF WILD TYPE OR HEREDITARY TRANSTHYRETIN-MEDIATED AMYLOIDOSIS (ATTR-CM)   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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