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Last Updated: March 28, 2024

Details for Patent: 8,648,087


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Which drugs does patent 8,648,087 protect, and when does it expire?

Patent 8,648,087 protects TUKYSA and is included in one NDA.

This patent has fifty-three patent family members in twenty-nine countries.

Summary for Patent: 8,648,087
Title:N4-phenyl-quinazoline-4-amine derivatives and related compounds as ErbB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases
Abstract: This invention provides compounds of Formula I ##STR00001## wherein B, G, A, E, R.sup.1, R.sup.2, R.sup.3, m and n are as defined herein, which are useful as type I receptor tyrosine kinase inhibitors, and methods of use thereof in the treatment of hyperproliferative disorders in mammals.
Inventor(s): Lyssikatos; Joseph P. (Piedmont, CA), Greschuk; Julie Marie (Erie, CO), Marmsater; Fredrik P. (Boulder, CO), Zhao; Qian (Superior, CO), Hennings; D. David (Loveland, CO), Liu; Weidong (Superior, CO)
Assignee: Array Biopharma, Inc. (Boulder, CO)
Application Number:12/085,048
Patent Claim Types:
see list of patent claims
Use; Composition; Compound; Process;

Drugs Protected by US Patent 8,648,087

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Seagen TUKYSA tucatinib TABLET;ORAL 213411-001 Apr 17, 2020 RX Yes No ⤷  Try a Trial ⤷  Try a Trial Y Y ⤷  Try a Trial
Seagen TUKYSA tucatinib TABLET;ORAL 213411-002 Apr 17, 2020 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,648,087

PCT Information
PCT FiledNovember 15, 2006PCT Application Number:PCT/US2006/044431
PCT Publication Date:May 24, 2007PCT Publication Number: WO2007/059257

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