Details for Patent: 8,648,087
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Which drugs does patent 8,648,087 protect, and when does it expire?
Patent 8,648,087 protects TUKYSA and is included in one NDA.
This patent has fifty-three patent family members in twenty-nine countries.
Summary for Patent: 8,648,087
Title: | N4-phenyl-quinazoline-4-amine derivatives and related compounds as ErbB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases |
Abstract: | This invention provides compounds of Formula I ##STR00001## wherein B, G, A, E, R.sup.1, R.sup.2, R.sup.3, m and n are as defined herein, which are useful as type I receptor tyrosine kinase inhibitors, and methods of use thereof in the treatment of hyperproliferative disorders in mammals. |
Inventor(s): | Lyssikatos; Joseph P. (Piedmont, CA), Greschuk; Julie Marie (Erie, CO), Marmsater; Fredrik P. (Boulder, CO), Zhao; Qian (Superior, CO), Hennings; D. David (Loveland, CO), Liu; Weidong (Superior, CO) |
Assignee: | Array Biopharma, Inc. (Boulder, CO) |
Application Number: | 12/085,048 |
Patent Claim Types: see list of patent claims | Use; Composition; Compound; Process; |
Drugs Protected by US Patent 8,648,087
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Seagen | TUKYSA | tucatinib | TABLET;ORAL | 213411-001 | Apr 17, 2020 | RX | Yes | No | ⤷ Try a Trial | ⤷ Try a Trial | Y | Y | ⤷ Try a Trial | |||
Seagen | TUKYSA | tucatinib | TABLET;ORAL | 213411-002 | Apr 17, 2020 | RX | Yes | Yes | ⤷ Try a Trial | ⤷ Try a Trial | Y | Y | ⤷ Try a Trial | |||
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 8,648,087
PCT Information | |||
PCT Filed | November 15, 2006 | PCT Application Number: | PCT/US2006/044431 |
PCT Publication Date: | May 24, 2007 | PCT Publication Number: | WO2007/059257 |
International Family Members for US Patent 8,648,087
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Austria | E446294 | ⤷ Try a Trial | |||
Austria | E507224 | ⤷ Try a Trial | |||
Australia | 2006315383 | ⤷ Try a Trial | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |