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Last Updated: February 26, 2024

Details for Patent: 8,637,533

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Summary for Patent: 8,637,533
Title:Inhibitors of human phosphatidylinositol 3-kinase delta
Abstract: Methods of inhibiting phosphatidylinositol 3-kinase delta isoform ( activity, and methods of treating diseases, such as disorders of immunity and inflammation, in which plays a role in leukocyte function are disclosed. Preferably, the methods employ active agents that selectively inhibit, while not significantly inhibiting activity of other PI3K isoforms. Compounds are provided that inhibit activity, including compounds that selectively inhibit activity. Methods of using inhibitory compounds to inhibit cancer cell growth or proliferation are also provided. Accordingly, the invention provides methods of using inhibitory compounds to inhibit processes in vitro and in vivo.
Inventor(s): Sadhu; Chanchal (Bothell, WA), Dick; Ken (Bothell, WA), Treiberg; Jennifer (Redmond, WA), Sowell; C. Gregory (Mukilteo, WA), Kesicki; Edward A. (Bothell, WA), Oliver; Amy (Bothell, WA)
Assignee: ICOS Corporation (Indianapolis, IN)
Application Number:13/399,828
Patent Claim Types:
see list of patent claims

Drugs Protected by US Patent 8,637,533

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
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