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Serving leading biopharmaceutical companies globally:

Moodys
UBS
Teva
Johnson and Johnson
Healthtrust
McKinsey
Mallinckrodt
Argus Health
Daiichi Sankyo
Queensland Health

Generated: January 18, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,633,219

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Which drugs does patent 8,633,219 protect, and when does it expire?

Patent 8,633,219 protects GENVOYA and STRIBILD and is included in two NDAs.

This patent has six patent family members in three countries.
Summary for Patent: 8,633,219
Title:Combination therapy
Abstract: The present invention relates to a combination therapy for treating an HIV infection or inhibiting integrase comprising (S)-6-(3-Chloro-2-fluorobenzyl)-1-(1-hydroxymethyl-2-methylpropyl)-7-meth- oxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ("Compound A") or a pharmaceutically acceptable solvate or salt thereof in combination with at least one other anti-HIV agent. In some embodiments of the present invention, the other anti-HIV agents are chosen from reverse transcriptase inhibitors and protease inhibitors. In certain embodiments of the present invention, the other anti-HIV agents are chosen from AZT, 3TC, PMPA, efavirenz, indinavir, nelfinavir, a combination of AZT/3TC, and a combination of PMPA/3TC. Since Compound A has a high inhibitory activity specific for integrases, when used in combinations with other anti-HIV agents it can provide a combination therapy with fewer side effects for humans.
Inventor(s): Matsuzaki; Yuji (Osaka, JP), Watanabe; Wataru (Osaka, JP), Ikeda; Satoru (Osaka, JP), Kano; Mitsuki (Osaka, JP)
Assignee: Japan Tobacco Inc. (Tokyo, JP)
Application Number:11/133,463
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 8,633,219

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Gilead Sciences Inc GENVOYA cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate TABLET;ORAL 207561-001 Nov 5, 2015 RX Yes Yes ➤ Subscribe ➤ Subscribe Y TREATMENT OF HIV INFECTION ➤ Subscribe
Gilead Sciences Inc STRIBILD cobicistat; elvitegravir; emtricitabine; tenofovir disoproxil fumarate TABLET;ORAL 203100-001 Aug 27, 2012 RX Yes Yes ➤ Subscribe ➤ Subscribe Y TREATMENT OF HIV INFECTION ➤ Subscribe
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 8,633,219

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Japan 4629104 ➤ Subscribe
Japan 2008500386 ➤ Subscribe
European Patent Office 2332538 ➤ Subscribe
European Patent Office 2229945 ➤ Subscribe
European Patent Office 1758581 ➤ Subscribe
World Intellectual Property Organization (WIPO) 2005112930 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

US Department of Justice
Cipla
AstraZeneca
Chinese Patent Office
Dow
Cerilliant
US Army
Citi
Medtronic

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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