Details for Patent: 8,623,868
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Summary for Patent: 8,623,868
Title: | Processes of making and using pharmaceutical formulations of antineoplastic agents |
Abstract: | In its several embodiments, this invention discloses a pharmaceutical formulation comprising at least one antineoplastic agent or a pharmaceutically acceptable salt thereof, and at least one dissolution enhancing agent sufficient to substantially dissolve said at least one antineoplastic agent in at least one aqueous diluent, wherein said dissolution enhancing agent is urea, L-histidine, L-threonine, L-asparagine, L-serine, L-glutamine or mixtures thereof; a lyophilized powder comprising said pharmaceutical formulation, and articles of manufacture thereof. |
Inventor(s): | Ugwu; Sydney (Gurnee, IL), Radhakrishnan; Vinay (Thousand Oaks, CA), Ihnat; Peter M. (Brooklyn, NY), Witchey-Lakshmanan; Lenore C. (Piscataway, NJ) |
Assignee: | Merck Sharp & Dohme Corp. (Rahway, NJ) |
Application Number: | 13/290,251 |
Patent Claim Types: see list of patent claims | Compound; |
Drugs Protected by US Patent 8,623,868
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International Family Members for US Patent 8,623,868
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Argentina | 038535 | ⤷ Try a Trial | |||
Argentina | 064722 | ⤷ Try a Trial | |||
Argentina | 084868 | ⤷ Try a Trial | |||
Austria | 397440 | ⤷ Try a Trial | |||
Australia | 2003213142 | ⤷ Try a Trial | |||
Brazil | 0307802 | ⤷ Try a Trial | |||
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