Details for Patent: 8,618,135
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Which drugs does patent 8,618,135 protect, and when does it expire?
Patent 8,618,135 protects JUXTAPID and is included in one NDA.
This patent has twenty-seven patent family members in eighteen countries.
Summary for Patent: 8,618,135
Title: | Methods for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side effects |
Abstract: | The present invention provides methods and compositions for treating hyperlipidemia and/or hypercholesterolemia comprising administering to the subject an effective amount of an MTP inhibitor to inhibit hyperlipidemia and/or hypercholesterolemia in said subject, wherein said administration comprises an escalating series of doses of the MTP inhibitor. In some embodiments the method comprises administering at least three step-wise, increasing dosages of the MTP inhibitor to the subject. In some embodiments, the method further comprises the administration of one or more other lipid modifying compounds. |
Inventor(s): | Rader; Daniel J. (Philadelphia, PA) |
Assignee: | The Trustees of the University of Pennsylvania (Philadelphia, PA) |
Application Number: | 13/046,118 |
Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 8,618,135 |
Patent Claim Types: see list of patent claims | Use; Delivery; |
Drugs Protected by US Patent 8,618,135
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chiesi | JUXTAPID | lomitapide mesylate | CAPSULE;ORAL | 203858-001 | Dec 21, 2012 | RX | Yes | No | ⤷ Sign Up | ⤷ Sign Up | A DOSING REGIMEN FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA AND HYPERLIPIDEMIA IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA USING AT LEAST THREE STEP-WISE INCREASING DOSES | ⤷ Sign Up | ||||
Chiesi | JUXTAPID | lomitapide mesylate | CAPSULE;ORAL | 203858-002 | Dec 21, 2012 | RX | Yes | No | ⤷ Sign Up | ⤷ Sign Up | A DOSING REGIMEN FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA AND HYPERLIPIDEMIA IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA USING AT LEAST THREE STEP-WISE INCREASING DOSES | ⤷ Sign Up | ||||
Chiesi | JUXTAPID | lomitapide mesylate | CAPSULE;ORAL | 203858-003 | Dec 21, 2012 | RX | Yes | No | ⤷ Sign Up | ⤷ Sign Up | A DOSING REGIMEN FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA AND HYPERLIPIDEMIA IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA USING AT LEAST THREE STEP-WISE INCREASING DOSES | ⤷ Sign Up | ||||
Chiesi | JUXTAPID | lomitapide mesylate | CAPSULE;ORAL | 203858-004 | Apr 23, 2015 | RX | Yes | No | ⤷ Sign Up | ⤷ Sign Up | A DOSING REGIMEN FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA AND HYPERLIPIDEMIA IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA USING AT LEAST THREE STEP-WISE INCREASING DOSES | ⤷ Sign Up | ||||
Chiesi | JUXTAPID | lomitapide mesylate | CAPSULE;ORAL | 203858-005 | Apr 23, 2015 | DISCN | Yes | No | ⤷ Sign Up | ⤷ Sign Up | A DOSING REGIMEN FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA AND HYPERLIPIDEMIA IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA USING AT LEAST THREE STEP-WISE INCREASING DOSES | ⤷ Sign Up | ||||
Chiesi | JUXTAPID | lomitapide mesylate | CAPSULE;ORAL | 203858-006 | Apr 23, 2015 | DISCN | Yes | No | ⤷ Sign Up | ⤷ Sign Up | A DOSING REGIMEN FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA AND HYPERLIPIDEMIA IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA USING AT LEAST THREE STEP-WISE INCREASING DOSES | ⤷ Sign Up | ||||
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,618,135
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
European Patent Office | 1725234 | ⤷ Sign Up | CA 2014 00002 | Denmark | ⤷ Sign Up |
European Patent Office | 1725234 | ⤷ Sign Up | C300634 | Netherlands | ⤷ Sign Up |
European Patent Office | 1725234 | ⤷ Sign Up | PA2014001 | Lithuania | ⤷ Sign Up |
European Patent Office | 1725234 | ⤷ Sign Up | C20140001 00107 | Estonia | ⤷ Sign Up |
European Patent Office | 1725234 | ⤷ Sign Up | 14C0003 | France | ⤷ Sign Up |
European Patent Office | 1725234 | ⤷ Sign Up | 1490006-2 | Sweden | ⤷ Sign Up |
European Patent Office | 1725234 | ⤷ Sign Up | 92349 | Luxembourg | ⤷ Sign Up |
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |